Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

9.8K
In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
9.8K
lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

3.5K
3.5K
Glaucoma: Overview01:25

Glaucoma: Overview

1.3K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.3K
Weighted Mean00:57

Weighted Mean

6.2K
While taking the arithmetic, geometric, or harmonic mean of a sample data set, equal importance is assigned to all the data points. However, all the values may not always be equally important in some data sets. An intrinsic bias might make it more important to give more weightage to specific values over others.
For example, consider the number of goals scored in the matches of a tournament. While computing the average number of goals scored in the tournament, it may be more important to...
6.2K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

969
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
969
Nursing Code of Ethics01:29

Nursing Code of Ethics

4.3K
The Nursing Code of Ethics sets the ethical benchmark for the profession, and guides nurses in ethical analysis and decision making at the societal, organizational, and clinical levels. The code encompasses showing compassion and respect for the patient, their families, and communities in all circumstances while committing to providing patient-centered care. In addition, the code states that nurses must advocate for the patient by defending a cause or recommendation to protect their rights,...
4.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Deep learning models for predicting opaque bubble layer morphology of keratorefractive lenticule extraction before laser scanning.

Advances in ophthalmology practice and research·2026
Same author

Multi-scale deformable attention fusion network with global context modeling for chest X-ray lesion segmentation.

BMC medical imaging·2026
Same author

Patch-sampled contrastive learning for dense prediction pretraining in metallographic images.

Scientific reports·2025
Same author

PMSFINet: Progressive Multi-Scale Feature Interaction Network for Medical Image Segmentation.

IEEE journal of biomedical and health informatics·2025
Same author

Management, Safety, and Efficacy Evaluation of Nutraceutical and Functional Food: A Global Perspective.

Comprehensive reviews in food science and food safety·2025
Same author

EMLFCL: An Efficient Multilevel Fusion Contrastive Learning for Multiview Clustering.

IEEE transactions on neural networks and learning systems·2025

Related Experiment Video

Updated: Jan 21, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.8K

Adaptive weighted locality-constrained sparse coding for glaucoma diagnosis.

Wei Zhou1, Yugen Yi2, Jining Bao3,4

  • 1College of Computer Science, Shenyang Aerospace University, Shenyang, Liaoning, China. zhouweineu@outlook.com.

Medical & Biological Engineering & Computing
|July 29, 2019
PubMed
Summary
This summary is machine-generated.

A new adaptive weighted locality-constrained sparse coding (AWLCSC) method improves glaucoma diagnosis by accurately estimating the vertical cup-to-disc ratio (CDR) from retinal images. This approach offers a more robust and effective solution for early detection of this sight-threatening disease.

Keywords:
Cup-to-disc ratioGlaucomaMultiple distance measurementsSparse coding

More Related Videos

FISH for Pre-implantation Genetic Diagnosis
07:34

FISH for Pre-implantation Genetic Diagnosis

Published on: February 23, 2011

37.8K
Ultrasound Cyclo Plasty in Eyes with Glaucoma
05:05

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

12.7K

Related Experiment Videos

Last Updated: Jan 21, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.8K
FISH for Pre-implantation Genetic Diagnosis
07:34

FISH for Pre-implantation Genetic Diagnosis

Published on: February 23, 2011

37.8K
Ultrasound Cyclo Plasty in Eyes with Glaucoma
05:05

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

12.7K

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Computer Vision

Background:

  • Glaucoma is a leading cause of irreversible blindness.
  • Accurate diagnosis relies on metrics like the vertical cup-to-disc ratio (CDR).
  • 2D retinal fundus images are crucial for automated glaucoma detection.

Purpose of the Study:

  • To introduce a novel sparse coding approach for glaucoma diagnosis.
  • To enhance the robustness and effectiveness of glaucoma diagnosis using retinal images.
  • To automate the estimation of the vertical cup-to-disc ratio (CDR) for improved diagnostic accuracy.

Main Methods:

  • Developed adaptive weighted locality-constrained sparse coding (AWLCSC).
  • Constructed a weighted matrix by adaptively fusing multiple distance measurements.
  • Extracted and reconstructed disc images using AWLCSC for CDR estimation.

Main Results:

  • The proposed AWLCSC method demonstrated superior performance compared to existing approaches.
  • Evaluated on DRISHTI-GS1 and RIM-ONE r2 databases, showing significant improvements.
  • Successfully automated the estimation of CDR from retinal fundus images.

Conclusions:

  • AWLCSC provides a robust and effective method for glaucoma diagnosis.
  • The approach offers automated CDR estimation, aiding in early detection.
  • Outperforms state-of-the-art methods, paving the way for advanced glaucoma screening.