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Related Experiment Videos

Unexpected and prolonged akinesia: a case report.

E B Fink

    The Journal of Clinical Psychiatry
    |November 1, 1978
    PubMed
    Summary

    A college student experienced prolonged akinesia after stopping low-dose neuroleptic medication. This case highlights the potential for extended extrapyramidal side effects, even after short-term treatment.

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    Area of Science:

    • Neuroscience
    • Pharmacology
    • Clinical Medicine

    Background:

    • Neuroleptic medications are frequently prescribed for various psychiatric conditions.
    • Extrapyramidal side effects (EPS) are known adverse reactions to neuroleptic drugs.
    • The duration and management of EPS following treatment cessation require further investigation.

    Observation:

    • A male college student presented with akinesia, a movement disorder characterized by a lack of voluntary movement.
    • The akinesia persisted for nearly three weeks.
    • This condition emerged after a brief period of low-dose neuroleptic treatment.

    Findings:

    • The case illustrates that akinesia can be a prolonged extrapyramidal side effect of neuroleptic withdrawal.
    • Review of existing literature indicates that the duration of such side effects can vary significantly.
    • These syndromes may be underdiagnosed or misdiagnosed in clinical practice.

    Implications:

    • Prolonged EPS can lead to significant patient distress and morbidity.
    • Accurate diagnosis and recognition of EPS are crucial for patient compliance and effective pharmacotherapy.
    • This case underscores the importance of monitoring for delayed adverse drug reactions.

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