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Biofunctionalization of Magnetic Nanomaterials
Published on: July 16, 2020
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2D Nanomaterials for Cancer Theranostic Applications
Liang Cheng1, Xianwen Wang1, Fei Gong1
1Institute of Functional Nano and Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou, 215123, China.
Advanced Materials (Deerfield Beach, Fla.)
|July 30, 2019
Summary
Two-dimensional (2D) nanomaterials offer unique properties for advanced nanomedicine, particularly in cancer theranostics. Their large surface area and tunable characteristics enable efficient drug delivery, imaging, and therapy.
Area of Science:
- Nanomedicine
- Materials Science
- Oncology
Background:
- Two-dimensional (2D) nanomaterials, including graphene, transition metal dichalcogenides, and others, have garnered significant interest due to their unique properties.
- Research into 2D nanomaterials for biomedical applications, especially in nanomedicine, has expanded rapidly over the past decade.
- These materials possess large surface areas and extraordinary physicochemical properties suitable for therapeutic and diagnostic applications.
Purpose of the Study:
- To summarize the latest advancements in the development and application of 2D nanomaterials for cancer theranostics.
- To discuss the potential of 2D nanomaterials in drug delivery, phototherapy, radiotherapy, and multimodal imaging for cancer treatment.
- To explore the current challenges and future perspectives of 2D nanomaterials in nanomedicine.
Main Methods:
- Review of recent scientific literature on 2D nanomaterials in nanomedicine and cancer theranostics.
- Analysis of the properties of various 2D nanomaterials (e.g., graphene, TMDs, MXenes, BP, LDH, MOFs).
- Discussion of integration strategies with other nanoparticles and inherent property utilization for theranostic applications.
Main Results:
- 2D nanomaterials serve as highly efficient nanoplatforms for drug delivery owing to their large surface area.
- Their optical and X-ray attenuation properties are valuable for phototherapy and radiotherapy of cancer.
- Engineered 2D nanomaterials show promise as nanoprobes for multimodal tumor imaging, contributing to cancer theranostics.
Conclusions:
- 2D nanomaterials demonstrate substantial potential for advancing cancer theranostic applications.
- Continued research and development are crucial to overcome current challenges and fully realize the clinical potential of these materials in nanomedicine.
- Future perspectives involve optimizing material design and integration for enhanced efficacy and safety in cancer diagnosis and treatment.
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