Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

1.3K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.3K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

969
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
969
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

1.3K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.3K
Cystic Fibrosis: Pathogenesis01:23

Cystic Fibrosis: Pathogenesis

738
Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
738
Pulmonary Hypertension: Classification and Pathogenesis01:30

Pulmonary Hypertension: Classification and Pathogenesis

591
Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
591
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

1.2K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ocular and Orbital Involvement in Extranodal Natural Killer/T-cell Lymphoma: A Systematic Review of Clinical Outcomes and Prognostic Factors.

Cureus·2026
Same author

Unilateral Panuveitis Secondary to Toxoplasmosis in an Immunocompromised Patient: A Case Report.

Cureus·2026
Same author

Ocular Lymphatics in Health and Disease.

Diagnostics (Basel, Switzerland)·2026
Same author

Pigmented paravenous retinochoroidal atrophy (PPRCA): a systematic review.

International ophthalmology·2026
Same author

Epstein-Barr Virus-Associated Primary Vitreoretinal B-Cell Lymphoma in a Patient Receiving Tofacitinib and Methotrexate for Psoriatic Arthritis.

Ocular immunology and inflammation·2026
Same author

Paediatric Retinal Detachment in a Patient With Coexistent Stickler and Noonan Syndromes: The Importance of a Multidisciplinary Approach.

Cureus·2026

Related Experiment Video

Updated: Jan 21, 2026

Ultrasound Cyclo Plasty in Eyes with Glaucoma
05:05

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

12.7K

Pathogenesis of Uveitic Glaucoma.

Dimitrios Kalogeropoulos1, Velota Ct Sung1

  • 1Birmingham and Midland Eye Centre, Sandwell and West Birmingham Hospital, NHS Trust, UK.

Journal of Current Glaucoma Practice
|July 30, 2019
PubMed
Summary
This summary is machine-generated.

Uveitic glaucoma, a rare complication of intraocular inflammation, is a leading cause of preventable vision loss. Understanding its complex pathogenesis, involving inflammation type and steroid response, is key to developing effective treatments and improving patient outcomes.

Keywords:
GlaucomaIntraocular pressureOcular hypertension/hypotonyOcular inflammationUveitic glaucomaUveitis

More Related Videos

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.8K
Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation
08:30

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Published on: March 12, 2016

13.6K

Related Experiment Videos

Last Updated: Jan 21, 2026

Ultrasound Cyclo Plasty in Eyes with Glaucoma
05:05

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

12.7K
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.8K
Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation
08:30

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Published on: March 12, 2016

13.6K

Area of Science:

  • Ophthalmology
  • Immunology
  • Glaucoma Research

Background:

  • Uveitic glaucoma is a severe complication of intraocular inflammation, contributing significantly to preventable blindness globally.
  • Its pathogenesis remains incompletely understood, though inflammation type, steroid responsiveness, and anterior chamber alterations are implicated.
  • Current management focuses on controlling inflammation and lowering intraocular pressure (IOP), presenting significant challenges for ophthalmologists.

Purpose of the Study:

  • To elucidate the complex pathogenesis of uveitic glaucoma.
  • To analyze the correlation between inflammatory responses and disease mechanisms.
  • To highlight potential therapeutic targets for improved treatment strategies.

Main Methods:

  • Review and analysis of existing literature on uveitic glaucoma pathogenesis.
  • Examination of the roles of inflammation type, steroid response, and ocular anatomy.
  • Discussion of current and potential future treatment modalities.

Main Results:

  • Pathogenesis involves both acute and chronic mechanisms influenced by inflammation characteristics and ocular changes.
  • Effective management requires prompt therapeutic decisions and often multidisciplinary collaboration.
  • Further research into pathogenesis may reveal novel therapeutic targets and approaches.

Conclusions:

  • Uveitic glaucoma is a complex condition requiring a comprehensive understanding of its inflammatory basis.
  • Prompt diagnosis and treatment, alongside interdisciplinary care, are crucial for managing this sight-threatening complication.
  • Continued investigation into pathogenetic mechanisms holds promise for advancing therapeutic interventions and surgical outcomes.