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Predictive Model for the Risk of Severe Acute Malnutrition in Children
Olivier Mukuku1, Augustin Mulangu Mutombo2, Lewis Kipili Kamona2
1Department of Research, Institut Supérieur des Techniques Médicales, Lubumbashi, Democratic Republic of the Congo.
Insights
A new scoring system can predict severe acute malnutrition (SAM) in children under 5. This tool identifies at-risk children, helping to reduce malnutrition and mortality in developing countries.
Area of Science:
- Pediatrics
- Nutritional Science
- Public Health
Background:
- Nutritional status is a key indicator of child well-being.
- Inadequate feeding practices significantly impact child development.
- Severe acute malnutrition (SAM) poses a major threat to children globally.
Purpose of the Study:
- To develop a predictive score for identifying children at risk of severe acute malnutrition (SAM).
- To create a simple and efficient clinical tool for early detection of malnutrition.
Main Methods:
- A case-control study involving 263 children aged 6-59 months with SAM.
- Univariate and multivariate analyses were performed.
- Receiver Operating Characteristic (ROC) curve and Hosmer-Lemeshow test were used to assess the score's discrimination and calibration.
Main Results:
- Nine predictive factors for SAM were identified, including low birth weight, diarrhea history, and early cessation of breastfeeding.
- A scoring system was developed: <6 points (low risk), 6-8 points (moderate risk), >8 points (high risk).
- The predictive score demonstrated high accuracy with an ROC area of 0.9685, 93.5% sensitivity, and 93.1% specificity.
Conclusions:
- A simple and effective predictive model for SAM risk in children under 5 has been developed.
- This tool can aid clinicians in identifying at-risk children in developing countries.
- The model aims to reduce malnutrition rates, disease, and child mortality.
Background:
The nutritional status is the best indicator of the well-being of the child. Inadequate feeding practices are the main factors that affect physical growth and mental development. The aim of this study was to develop a predictive score of severe acute malnutrition (SAM) in children under 5 years of age.
Methods:
It was a case-control study. The case group (n = 263) consisted of children aged 6 to 59 months admitted to hospital for SAM that was defined by a z-score weight/height < -3 SD or presence of edema of malnutrition. We performed a univariate and multivariate analysis. Discrimination score was assessed using the ROC curve and the calibration of the score by Hosmer-Lemeshow test.
Results:
Low birth weight, history of recurrent or chronic diarrhea, daily meal's number less than 3, age of breastfeeding's cessation less than 6 months, age of introduction of complementary diets less than 6 months, maternal age below 25 years, parity less than 5, family history of malnutrition, and number of children under 5 over 2 were predictive factors of SAM. Presence of these nine criteria affects a certain number of points; a score <6 points defines children at low risk of SAM, a score between 6 and 8 points defines a moderate risk of SAM, and a score >8 points presents a high risk of SAM. The area under ROC curve of this score was 0.9685, its sensitivity was 93.5%, and its specificity was 93.1%.
Conclusion:
We propose a simple and efficient prediction model for the risk of occurrence of SAM in children under 5 years of age in developing countries. This predictive model of SAM would be a useful and simple clinical tool to identify people at risk, limit high rates of malnutrition, and reduce disease and child mortality registered in developing countries.
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