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Updated: Jan 21, 2026

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
Arterial Calcification on Wrist Radiographs May Suggest Need for Evaluation of Atherosclerosis in Asymptomatic
Lauren E Watchmaker1, Jennifer M Watchmaker2, Greg P Watchmaker3
1University of Wisconsin School of Medicine and Public Health, 750 Highland Ave, Madison, WI 53726, USA.
Insights
Peripheral arterial calcifications on hand X-rays may indicate significant coronary artery disease (CAD) risk in asymptomatic individuals. This finding suggests hand X-rays could help identify patients needing further cardiac evaluation for atherosclerosis.
Area of Science:
- Cardiology
- Radiology
- Vascular Medicine
Background:
- Asymptomatic individuals with significant coronary artery disease (CAD) face risks of unexpected cardiac events like myocardial infarction (MI).
- Current diagnostic methods for at-risk individuals include laboratory tests, stress tests, and coronary artery imaging, such as coronary artery calcium (CAC) scoring.
Observation:
- Radiographs of hands and wrists showing substantial arterial wall calcification may serve as an additional indicator for identifying at-risk asymptomatic individuals.
- A case series identified patients without known heart disease who exhibited significant calcium deposits in radial and/or ulnar arteries on radiographs taken for hand condition evaluations.
Findings:
- All patients in the case series were subsequently found to have coronary artery calcification on imaging.
- These patients also presented an elevated risk for future cardiac events.
Implications:
- The presence of peripheral arterial calcifications, as observed by radiologists and hand specialists, may signal the need for a comprehensive systemic evaluation for atherosclerosis.
- This approach could enhance early detection and management of cardiovascular disease in asymptomatic populations.
Abstract:
Asymptomatic individuals with significant coronary artery disease (CAD) are at risk for unanticipated cardiac events including myocardial infarction (MI). Laboratory studies, stress tests, and coronary artery imaging including coronary artery calcium (CAC) scoring evaluate at-risk individuals. Hand and wrist x-rays demonstrating significant arterial wall calcification may provide an additional means to identify asymptomatic individuals at risk for cardiac events. Here we report a case series of patients without known cardiac disease who demonstrated significant calcium deposits in the radial and/or ulnar arteries in radiographs performed for evaluation of their hand conditions. Each series patient was subsequently found to have calcification on coronary artery imaging and an elevated risk of future cardiac events. Our series suggests that peripheral arterial calcifications observed by radiologists and hand specialists may warrant systemic evaluation for atherosclerosis in other areas of the body.
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