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Published on: April 19, 2017
Prevalence of Anemia and Its Associated Risk Factors Among 6-Months-Old Infants in Beijing
Qinrui Li1, Furong Liang1, Weilan Liang1
1Department of Pediatrics, Peking University First Hospital, Beijing, China.
Insights
Infant anemia is linked to premature birth, exclusive breastfeeding, lack of complementary foods, and spring birth. Early detection and intervention are crucial for infant health and development.
Area of Science:
- Pediatrics
- Nutritional Science
- Public Health
Background:
- Anemia affects approximately 24.8% globally, with iron deficiency anemia posing risks to children's development.
- Early detection and intervention for infant anemia are critical to prevent long-term sensory, motor, cognitive, language, and socioemotional deficits.
Purpose of the Study:
- To identify risk factors associated with anemia in 6-month-old infants to inform prevention strategies.
- To investigate the relationship between various infant and maternal factors and the prevalence of anemia.
Main Methods:
- A cross-sectional study was conducted on 1,127 infants aged 6 months at Peking University First Hospital.
- Data collected included birth information, maternal demographics, feeding practices (breastfeeding, formula, complementary foods), and caregiver type.
- Infant development was assessed using the Denver Developmental Screening Test (DDST).
Main Results:
- The prevalence of anemia among the studied infants was 11.8%.
- Risk factors for anemia included premature birth (gestational age <37 weeks), birth during autumn/winter, exclusive breastfeeding, and lack of complementary foods.
- Birth weight and caregiver type did not significantly affect anemia rates. DDST pass rates were similar between anemic and non-anemic infants.
Conclusions:
- Key risk factors for infant anemia identified were: gestational age <37 weeks, exclusive breastfeeding, absence of complementary foods, and spring birth.
- These findings highlight the importance of targeted interventions for at-risk infants.
- No developmental deficits were detected by DDST in anemic infants at 6 months, underscoring the need for continued monitoring.
Abstract:
Objective: The worldwide prevalence of anemia is ~24.8%. Iron deficiency anemia is common in children and women and associated with sensory, motor, cognitive, language, and socioemotional deficits. Therefore, detection and early intervention strategies for anemia in infants are urgently needed. To prevent the occurrence of iron deficiency anemia, we aimed to identify risk factors associated with anemia in infants. Methods: This investigation involved a cross-sectional study of 6-months-old infants discharged between April 2014 and September 2017 from Peking University First Hospital. We assessed birth information, maternal age, and maternal educational level as well as data on feeding style, complementary foods and primary caregivers. The infants were assessed with the Denver Developmental Screening Test (DDST). Results: A total of 1,127 6-months-old infants were enrolled at the hospital. We found that the prevalence of anemia among infants in Beijing was ~11.8%. Premature infants had a higher rate of anemia than full-term infants (χ2 = 40.103, P < 0.001). Infants born in autumn or winter were at an elevated risk of developing anemia (χ2 = 22.949, P < 0.001). Birth weight had no effect on the rate of anemia in infants (χ2 = 0.023, P = 0.568). Infants who were exclusively breastfeeding had higher anemia rates than those who were fed formula (χ2 = 38.466, P < 0.001). Infants whose caregivers added no complementary foods had higher anemia rates (24.7%) than those whose caregivers added more than two kinds of complementary food (8.2%). The type of caregiver had no effect on the anemia rate in infants (χ2 = 0.031, P = 1.000). Conclusions: The following factors resulted in a higher prevalence of anemia in our study a gestational age at birth of <37 weeks, exclusive breastfeeding, a lack of supplementation with complementary foods and a spring birth date. No significant differences in DDST pass rates were evident between infants with and without anemia.
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