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Asthma-I: Introduction

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...

Asthma-II: Pathophysiology and Classification

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:

Asthma: Pathogenesis and Management

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.

Asthma-III: Symptoms and Complications

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma

Asthma-IV: Diagnostic and Management

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:

Asthma-IV: Nursing Management

Asthma-IV: Nursing Management

The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...

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A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion

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Published on: May 12, 2023

Immunomodulation in Pediatric Asthma.

Amelia Licari¹, Sara Manti^2,3, Riccardo Castagnoli¹

¹Department of Pediatrics, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.

Frontiers in Pediatrics

|July 30, 2019

Summary

Childhood asthma is a complex disease. This review explores new biologic therapies that target underlying inflammation, offering hope for severe cases unresponsive to standard inhaled corticosteroids (ICS).

Keywords:

asthma biologics children endotypes mepolizumab omalizumab treatment

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Area of Science:

Pediatric Pulmonology
Immunology
Pharmacology

Background:

Childhood asthma is a heterogeneous respiratory disease with diverse immune mechanisms.
Current management focuses on symptom control and risk reduction using inhaled corticosteroids (ICS) and controllers.
Standard therapies are not disease-modifying and are often ineffective for severe, uncontrolled pediatric asthma.

Purpose of the Study:

To review current and emerging therapeutic strategies for pediatric asthma.
To focus on immunomodulatory treatments, particularly biologic therapies.
To update knowledge on targeting specific inflammatory pathways in pediatric asthma.

Main Methods:

Literature review of current and novel asthma treatments.
Focus on immunomodulatory and biologic therapies.
Analysis of therapeutic options for pediatric asthma management.

Main Results:

Standard therapies like ICS offer symptom control but do not modify disease progression.
Severe pediatric asthma often remains uncontrolled with current treatments.
Biologic therapies represent a promising avenue for targeted immunomodulation.

Conclusions:

Novel biologic therapies show potential for modifying pediatric asthma.
Targeting specific inflammatory pathways is crucial for severe cases.
Further research into immunomodulatory treatments is warranted for better asthma control.