CSF parameters associated with early MRI activity in patients with MS

Ana Klein1, Rebecca C Selter1, Alexander Hapfelmeier1

  • 1Department of Neurology (A.K., R.C.S., A.B., V.P., C.G., M.M., B.H.), Klinikum rechts der Isar, Medical Faculty, Technical University of Munich; Institute of Medical Informatics (A.H.), Statistics and Epidemiology, Medical Faculty, Technical University of Munich; Max Planck Institute of Psychiatry (B.M.-M.), Munich; Department of Neuroradiology (C.Z.), Klinikum rechts der Isar, Medical Faculty, Technical University of Munich; TUM Neuroimaging Center (M.M.), Klinikum rechts der Isar, Medical Faculty, Technical University of Munich; and Munich Cluster for Systems Neurology (SyNergy) (B.H.), Germany.

Summary

Cerebrospinal fluid (CSF) IgG and IgM indices predict future MRI activity in early multiple sclerosis (MS) and clinically isolated syndrome (CIS). These biomarkers can aid early treatment decisions for MS and CIS patients.

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