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A novel "signal on" photoelectrochemical strategy based on dual functional hemin for microRNA assay
Ling-Ying Xia1, Meng-Jie Li1, Hai-Jun Wang1
1Key Laboratory of Luminescence and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China. yuanruo@swu.edu.cn yaqinchai@swu.edu.cn.
Chemical Communications (Cambridge, England)
|July 30, 2019
Abstract:
In this work, a novel "signal on" photoelectrochemistry (PEC) biosensor was constructed with dual-functional hemin as a signal quencher and electronic mediator for ultrasensitive target microRNA-141 assay with the assistance of T7 exonuclease (Exo)-initiated target amplification technology.