Related Experiment Video
Updated: Jan 21, 2026

Implantation of Human-Sized Coronary Stents into Rat Abdominal Aorta Using a Trans-Femoral Access
Published on: November 19, 2020
Coronary stent implantation for acute basilar artery occlusion with underlying stenosis
Sándor Nardai1, Balázs Kis, István Gubucz
1Department Section of Neurointervention, Semmelweis University Department of Neurosurgery, National Institute of Clinical Neurosciences, Budapest, Hungary.
Insights
Coronary stent implantation during endovascular treatment for basilar artery occlusion with intracranial atherosclerotic stenosis improves survival and functional outcomes. This intervention reduces residual stenosis and enhances recovery chances.
Area of Science:
- Neuroendovascular therapy
- Cerebrovascular diseases
- Interventional neurology
Background:
- Acute basilar artery occlusion (BAO) with underlying intracranial atherosclerotic stenosis (ICAS) presents significant challenges.
- Standard endovascular treatment (EVT) outcomes for BAO with ICAS are often suboptimal.
Purpose of the Study:
- To evaluate the effectiveness of immediate coronary stent implantation during EVT for BAO with ICAS.
- To assess the impact of stenting on clinical outcomes, including survival and functional recovery.
Main Methods:
- Retrospective analysis of 91 BAO patients undergoing EVT.
- Comparison of outcomes between patients with and without ICAS.
- Assessment of stenting versus non-stenting in BAO-ICAS patients.
Main Results:
- BAO patients with ICAS had longer reperfusion times, lower reperfusion rates, and higher mortality compared to those without ICAS.
- Stenting in BAO-ICAS patients significantly reduced residual stenosis.
- Patients treated with stents showed higher chances of functional recovery and survival.
Conclusions:
- Immediate coronary stent implantation in BAO with underlying ICAS improves overall survival.
- Stenting combined with dual antiplatelet therapy (DAPT) leads to better functional outcomes in these patients.
Aims:
Our aim was to study the effectiveness of coronary stent implantation during the endovascular treatment (EVT) of acute basilar artery occlusion (BAO) with occlusion-underlying intracranial atherosclerotic stenosis (ICAS).
Methods And Results:
We retrospectively analysed 91 consecutive BAO patients who underwent EVT between February 2014 and January 2019 in a single, high-volume neurointerventional centre. We studied the effect of immediate coronary stent implantation on the clinical outcome of BAO with occlusion-underlying stenosis. BAO patients with underlying ICAS (n=41) were characterised by longer symptom-onset-to-reperfusion times (231 min vs 173 min, p=0.0020), lower TICI 2b-3 reperfusion rates (65.85% vs 90.00%, p=0.0084), and higher overall mortality (HR 2.021, p=0.0417) compared to the BAO cases without ICAS (n=50). The patients undergoing stenting (n=18) had lower residual basilar artery (BA) stenosis (14.7% vs 81.0%, p<0.0001), higher chance for functional recovery (OR 7.6, p=0.0250) and higher chance of survival (HR 4.163, p=0.0026) compared to the BAO-ICAS cases treated without coronary stents (n=21).
Conclusions:
The immediate treatment of the occlusion-underlying stenosis with coronary stents and dual antiplatelet therapy (DAPT) in BAO was associated with improved overall survival and better functional outcomes.
Related Concept Videos
Acute Coronary Syndrome I: Introduction
Coronary Artery Disease I: Introduction
Coronary Artery Disease II: Pathophysiology
Acute Coronary Syndrome V: Nursing Management
Coronary Artery Disease V: Interprofessional Care
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

