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Updated: Jan 21, 2026

Assessment of Bone Fracture Healing Using Micro-Computed Tomography
Published on: December 9, 2022
Extending the dynamic range of biomedical micro-computed tomography for application to geomaterials
D R Edey1,2, S I Pollmann1, D Lorusso1,3
1Imaging Research Laboratories, Robarts Research Institute, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada.
This study introduces a simple correction method to reduce artifacts in biomedical micro-CT scans of dense objects. The new technique improves image accuracy for radiodense samples, enhancing 3D imaging capabilities.
Area of Science:
- Medical Imaging
- Materials Science
- Physics
Background:
- X-ray computed tomography (CT) provides non-destructive 3D imaging.
- Biomedical micro-CT scanners are increasingly accessible.
- CT images of dense objects suffer from beam hardening artifacts.
Purpose of the Study:
- To propose and evaluate a semi-empirical correction method for beam hardening and scatter in biomedical micro-CT.
- To improve the accuracy of CT imaging for dense and radiodense samples.
Main Methods:
- Designed and constructed novel calibration phantoms from aluminum and poly[methyl-methacrylate].
- Imaged phantoms using two biomedical micro-CT scanners.
- Applied semi-empirical linearization to projection data before image reconstruction.
Main Results:
- The proposed correction method effectively reduced beam hardening artifacts on both scanners.
- Polynomial correction using an aluminum phantom yielded the best results.
- Accurate percent-volume composition of metallic inclusions in a meteorite sample was achieved.
Conclusions:
- Semi-empirical linearization with custom calibration phantoms enables accurate measurements on radiodense samples.
- The proposed correction method enhances the reliability of biomedical micro-CT imaging for dense materials.
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