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Adenosquamous Carcinoma Arising in Bulbar Conjunctiva
1Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Ophthalmic Plastic and Reconstructive Surgery
|July 30, 2019
Summary
Adenosquamous carcinoma, a rare and aggressive ocular tumor, was successfully treated in a patient. Surgical resection followed by topical interferon therapy prevented recurrence over a 12-month follow-up.
Area of Science:
- Ophthalmology
- Oncology
- Pathology
Background:
- Adenosquamous carcinoma is an aggressive malignancy with rare occurrence on the ocular surface.
- Early and accurate diagnosis is crucial for effective management of ocular tumors.
Observation:
- A patient presented with a conjunctival mass clinically suspected to be squamous cell carcinoma.
- The lesion measured 5 mm on the temporal conjunctiva.
Findings:
- Surgical resection with cryopexy of conjunctival wound edges was performed.
- Histopathology and immunoreactivity confirmed the diagnosis of ocular surface adenosquamous carcinoma.
- Post-operative topical interferon alpha 2b treatment was administered for 3 months.
Implications:
- This case highlights a successful treatment strategy for ocular surface adenosquamous carcinoma.
- Topical interferon alpha 2b may be an effective adjuvant therapy to prevent recurrence.
- Further research is warranted to establish optimal treatment protocols for this rare condition.
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