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Related Concept Videos

Energy Stored in a Capacitor01:12

Energy Stored in a Capacitor

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When an archer pulls the string in a bow, he saves the work done in the form of elastic potential energy. When he releases the string, the potential energy is released as kinetic energy of the arrow. A capacitor works on the same principle in which the work done is saved as electric potential energy. The potential energy (UC) could be calculated by measuring the work done (W) to charge the capacitor.
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Energy Stored in Capacitors01:10

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A parallel plate capacitor, when connected to a battery, develops a potential difference across its plates. This potential difference is key to the operation of the capacitor, as it determines how much electrical energy the capacitor can store.
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Energy Stored in Inductors01:16

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An inductor is ingeniously crafted to accumulate energy within its magnetic field. This field is a direct result of the current that meanders through its coiled structure. When this current maintains a steady state, there is no detectable voltage across the inductor, prompting it to mimic the behavior of a short circuit when faced with direct current.
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Energy Stored in a Capacitor: Problem Solving01:26

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In 1749, Benjamin Franklin coined the word battery for a series of capacitors connected to store energy. Capacitors store electric potential energy that can be released over a short time. This property means capacitors have a wide range of applications.
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Related Experiment Video

Updated: Jan 21, 2026

Procoagulant Platelet Characterization by Measuring Phosphatidylserine Exposure and Microvesicle Release from Human Purified Platelets
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Melatonin is not stored in platelets.

Martijn van Faassen1, Marloes A M Peters2, Annemiek M Walenkamp2

  • 1Department of Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

Clinica Chimica Acta; International Journal of Clinical Chemistry
|July 30, 2019
PubMed
Summary

This study found no evidence that platelets store melatonin. Advanced LC-MS/MS and ELISA methods confirmed melatonin levels in platelet-rich and platelet-poor plasma did not differ significantly.

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Area of Science:

  • Biochemistry
  • Hematology
  • Pharmacology

Background:

  • Platelets are known to store various biologically active compounds.
  • Melatonin's association with several diseases has increased interest in its presence within platelets.
  • Accurate quantification of platelet melatonin is crucial for understanding its physiological and pathological roles.

Purpose of the Study:

  • To definitively confirm or refute the storage of melatonin within human platelets.
  • To compare the efficacy of ELISA and LC-MS/MS for melatonin quantification in plasma.
  • To establish reliable methods for assessing platelet-derived melatonin.

Main Methods:

  • Melatonin concentrations were measured in platelet-rich plasma (PRP) and platelet-poor plasma (PPP) from 19 healthy volunteers.
  • Sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) and ELISA were employed for analysis.
  • Statistical analysis included Wilcoxon signed-rank test and Passing-Bablok regression for method comparison.

Main Results:

  • LC-MS/MS and ELISA methods showed poor agreement for melatonin quantification.
  • No statistically significant difference in melatonin levels was observed between PRP and PPP using either method (P = 0.89 for LC-MS/MS, P = 0.53 for ELISA).
  • These findings indicate no detectable storage of melatonin in platelets.

Conclusions:

  • The study provides no evidence supporting the hypothesis that human platelets store melatonin.
  • The discrepancy between ELISA and LC-MS/MS highlights the importance of method validation in melatonin analysis.
  • Further research may be needed to explore indirect roles of melatonin in platelet function or related disease mechanisms.