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PLD1 promotes dendritic spine morphogenesis via activating PKD1

Wen-Qi Li1, Li-Da Luo1, Zhi-Wen Hu1

  • 1Neuroscience Research Institute and Department of Neurobiology, School of Basic Medical Sciences, Key Laboratory for Neuroscience, Ministry of Education, National Health Commission and State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100083, China.

Molecular and Cellular Neurosciences
|July 30, 2019
PubMed
Summary

Phospholipase D1 (PLD1) activates protein kinase D1 (PKD1), promoting dendritic spine development crucial for brain function. This discovery sheds light on neuronal development and related neurological disorders.

Keywords:
Dendritic spine morphogenesisPhospholipase D1 (PLD1)Protein kinase D1 (PKD1)

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