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Current status of optical fiber biosensor based on surface plasmon resonance
Yong Zhao1, Rui-Jie Tong2, Feng Xia2
1State Key Laboratory of Synthetical Automation for Process Industries, Shenyang, 110819, China; College of Information Science and Engineering, Northeastern University, Shenyang, 110819, China.
Biosensors & Bioelectronics
|July 30, 2019
Summary
This review details fiber optic biosensors utilizing surface plasmon resonance (SPR) technology for enhanced sensing in life sciences and diagnostics. It covers SPR generation, device prototypes, and performance improvements for advanced biosensing applications.
Area of Science:
- Optoelectronics
- Biomedical Engineering
- Chemical Sensing
Background:
- Surface plasmon resonance (SPR) is a powerful optical phenomenon for label-free biosensing.
- Optic fiber technology offers miniaturization and remote sensing capabilities.
- Combining SPR with optic fibers creates highly sensitive biosensor platforms.
Purpose of the Study:
- To review the current research status of fiber optic biosensors based on SPR.
- To analyze the development and merits of SPR-based optic fiber sensors.
- To identify key challenges and future directions in this field.
Main Methods:
- Review of literature on SPR generation devices and optic fiber substrates.
- Detailed outline of different fiber optic SPR biosensor prototypes (grating and structured types).
- Comparison of sensing performance and discussion of multi-parameter detection strategies.
Main Results:
- Optical fiber is established as a suitable substrate for SPR generation.
- Various fiber optic SPR biosensor designs, including grating and structured types, are presented with recent advancements.
- Strategies for improving sensitivity and enabling simultaneous multi-parameter detection are summarized.
Conclusions:
- Fiber optic SPR biosensors represent a valuable and advancing research area.
- Key challenges include optimizing sensor design and enhancing detection capabilities.
- Future development should focus on integrated systems and broader applications in diagnostics and safety.
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