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Post-convulsive lactic acidosis in diabetic patients
1Diabetic Clinic, General Hospital, Birmingham, UK.
Annals of Clinical Biochemistry
|May 1, 1988
Summary
Diabetic individuals are more prone to seizures, which can lead to lactic acidosis. This condition often resolves on its own and specific treatments may be harmful.
Area of Science:
- Neurology
- Endocrinology
- Critical Care Medicine
Background:
- Diabetic patients face a higher risk of epileptic seizures compared to the general population.
- Generalized seizures can precipitate a severe lactic acidosis, a metabolic derangement.
Observation:
- Two cases of diabetic patients experiencing lactic acidosis post-seizure are presented.
- The underlying cause of lactic acidosis was identified retrospectively in both instances.
Findings:
- Post-seizure lactic acidosis in diabetics is a self-correcting condition.
- Specific interventions for this type of lactic acidosis are unnecessary and potentially dangerous.
Implications:
- Highlights the importance of recognizing self-limiting metabolic changes post-seizure in diabetic patients.
- Suggests caution against aggressive treatment for post-convulsive lactic acidosis in this population.
- Emphasizes the need for careful retrospective diagnosis to avoid iatrogenic harm.