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RACK1 affects the progress of G2/M by regulating Aurora-A

Suqin Shen1, Huan Feng1, Yichen Le1

  • 1State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University , Shanghai , P. R. China.

Cell Cycle (Georgetown, Tex.)
|July 31, 2019
PubMed
Summary

Receptor of activated C-kinase1 (RACK1) interacts with Aurora-A kinase, a protein overexpressed in cancers. RACK1 regulates Aurora-A activity, impacting cell division and potentially offering new anticancer targets.

Keywords:
Aurora-AG2/MMitosisPhosphorylationRACK1

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