Cerebral Aneurysms due to Cardiac Myxoma

Cerebral aneurysms due to cardiac myxoma has been sporadically reported; however, the clinical features of this entity has not been fully elucidated. This meta-analysis was conducted to determine the reported clinical features and outcomes of this condition. It revealed a predominance of cardiac myxoma-related multiple fusiform aneurysms of the middle cerebral artery. The cerebral aneurysms developed at a mean of 53 months after cardiac myxoma resection. Left atrial myoxma was the most common causing cerebral aneurysm than a myxoma arising from any other sites of the heart. Most patients with myxoma-related cerebral aneurysms were under follow-up, conservative, or surgical treatments. Patients' outcomes were promising, with 69.4% (34/49) patients being stable. The overall mortality rate was 4.1% (2/49), and long-term survival seemed to be satisfactory. Cardiac myxoma resection cannot avoid the occurrence of cerebral aneurysm; therefore, cerebroimaging monitoring is recommended even after cardiac myxoma resection.