Related Experiment Video
Updated: Jan 21, 2026

07:27
Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
Published on: August 25, 2021
2.3K
Predicting visual outcome after open globe injury using classification and regression tree model: the Moradabad
Richa Gupta1, Surabhi Gupta2, Lokesh Chauhan2
1C L Gupta Eye Institute, Ram Ganga Vihar, Phase 2, Moradabad, India..
Summary
Identifying factors for visual outcome in open globe injuries (OGIs) is crucial. Key predictors of vision loss include relative afferent pupillary defect (RAPD) and poor presenting visual acuity.
Area of Science:
- Ophthalmology
- Trauma Surgery
Background:
- Open globe injuries (OGIs) represent a significant cause of vision loss worldwide.
- Predicting visual outcomes in OGI patients is essential for effective management.
Purpose of the Study:
- To identify factors associated with visual outcomes in patients with open globe injuries.
- To evaluate the predictive capability of the Classification and Regression Tree (CART) model for visual prognosis in OGI.
Main Methods:
- Retrospective case series of 157 patients with OGIs presenting to a tertiary eye care institute.
- Multivariate analysis using binomial logistic regression and CART model for outcome prediction.
- Assessment of visual outcomes, risk factors, and postoperative complications.
Main Results:
- Univariate analysis identified 9 predictors of poor visual outcome.
- Relative afferent pupillary defect (RAPD), poor presenting visual acuity, adnexal injuries, and injury location were significant predictors of vision loss.
- Absence of RAPD correlated with a 79% chance of vision survival; 68% of patients with RAPD and initial visual acuity <6/60 had poor vision.
Conclusions:
- The CART model effectively predicts final visual acuity based on initial prognostic factors.
- Identifying key risk factors like RAPD and presenting visual acuity can guide OGI management and improve visual outcomes.
Related Concept Videos
Predicting Reaction Outcomes
10.3K
Kinetics describes the rate and path by which a reaction occurs. In contrast, thermodynamics deals with state functions and describes the properties, behavior, and components of a system. It is not concerned with the path taken by the process and cannot address the rate at which a reaction occurs. Although it does provide information about what can happen during a reaction process, it does not describe the detailed steps of what appears on an atomic or a molecular level. On the other hand,...
10.3K
Regression Toward the Mean
6.9K
Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when...
6.9K
The Tree of Life - Bacteria, Archaea, Eukaryotes
37.9K
The “tree of life” describes the evolution of life and the evolutionary relationships between organisms. The root of the tree is the common ancestor to all life on Earth. All other species radiate from this point, much like the branches of a tree. The numerous tips of these branches on the tree of life represent every living, or extant, species. Extinct species, which are species that no longer exist, can be found towards the center of the tree. Currently, these organisms, both...
37.9K
Multiple Regression
3.8K
Multiple regression assesses a linear relationship between one response or dependent variable and two or more independent variables. It has many practical applications.
Farmers can use multiple regression to determine the crop yield based on more than one factor, such as water availability, fertilizer, soil properties, etc. Here, the crop yield is the response or dependent variable as it depends on the other independent variables. The analysis requires the construction of a scatter plot...
Farmers can use multiple regression to determine the crop yield based on more than one factor, such as water availability, fertilizer, soil properties, etc. Here, the crop yield is the response or dependent variable as it depends on the other independent variables. The analysis requires the construction of a scatter plot...
3.8K
Correlation and Regression
3.1K
In statistics, correlation describes the degree of association between two variables. In the subfield of linear regression, correlation is mathematically expressed by the correlation coefficient, which describes the strength and direction of the relationship between two variables. The coefficient is symbolically represented by 'r' and ranges from -1 to +1. A positive value indicates a positive correlation where the two variables move in the same direction. A negative value suggests a...
3.1K
Regression Analysis
8.1K
Regression analysis is a statistical tool that describes a mathematical relationship between a dependent variable and one or more independent variables.
In regression analysis, a regression equation is determined based on the line of best fit– a line that best fits the data points plotted in a graph. This line is also called the regression line. The algebraic equation for the regression line is called the regression equation. It is represented as:
In regression analysis, a regression equation is determined based on the line of best fit– a line that best fits the data points plotted in a graph. This line is also called the regression line. The algebraic equation for the regression line is called the regression equation. It is represented as:
8.1K

