The ESC ACCA EAPCI EORP acute coronary syndrome ST-elevation myocardial infarction registry
Uwe Zeymer1, Peter Ludman2, Nicolas Danchin3
1Hospital of the City of Ludwigshafen, Medical Clinic B and Institute of Heart Attack Research, Ludwigshafen on the Rhine, Germany.
Insights
This study assessed reperfusion therapy use and guideline adherence in ST-elevation myocardial infarction (STEMI) patients across Europe. Findings offer insights into current STEMI care and outcomes.
Area of Science:
- Cardiology
- Clinical Research
- Public Health
Background:
- The European Society of Cardiology (ESC) provides guidelines for ST-elevation myocardial infarction (STEMI) management.
- Reperfusion therapy is crucial for STEMI patients, aiming to restore blood flow to the heart muscle.
- Understanding current practices and guideline adherence is essential for improving STEMI care.
Purpose of the Study:
- To evaluate the current use of reperfusion therapy in STEMI patients within ESC member and affiliated countries.
- To assess adherence to ESC STEMI guidelines regarding reperfusion and adjunctive treatments.
- To describe demographic, clinical, and angiographic characteristics of STEMI patients and their 1-year outcomes.
Main Methods:
- The study enrolled 11,462 STEMI patients from 196 centers across 29 countries between January 2015 and March 2018.
- Data collection included patient demographics, clinical presentation, angiographic findings, and treatment strategies.
- A 1-year follow-up was planned to assess patient outcomes.
Main Results:
- The registry captured data on 11,462 STEMI patients, providing a comprehensive overview of contemporary STEMI care.
- Analysis focused on reperfusion strategies, adjunctive therapies, and adherence to 2012 ESC STEMI guidelines.
- The study aimed to correlate treatment patterns with patient outcomes over a 1-year period.
Conclusions:
- The ESC ACCA-EAPCI EORP ACS STEMI registry offers valuable insights into STEMI patient profiles and management.
- It highlights current reperfusion therapy use and guideline adherence in clinical practice.
- The registry will elucidate the impact of contemporary management on 1-year outcomes for STEMI patients.
Aims:
The Acute Cardiac Care Association (ACCA)-European Association of Percutaneous Coronary Intervention (EAPCI) Registry on ST-elevation myocardial infarction (STEMI) of the EurObservational programme (EORP) of the European Society of Cardiology (ESC) registry aimed to determine the current state of the use of reperfusion therapy in ESC member and ESC affiliated countries and the adherence to ESC STEMI guidelines in patients with STEMI.
Methods And Results:
Between 1 January 2015 and 31 March 2018, a total of 11 462 patients admitted with an initial diagnosis of STEMI according to the 2012 ESC STEMI guidelines were enrolled. Individual patient data were collected across 196 centres and 29 countries. Among the centres, there were 136 percutaneous coronary intervention centres and 91 with cardiac surgery on-site. The majority of centres (129/196) were part of a STEMI network. The main objective of this study was to describe the demographic, clinical, and angiographic characteristics of patients with STEMI. Other objectives include to assess management patterns and in particular the current use of reperfusion therapies and to evaluate how recommendations of most recent STEMI European guidelines regarding reperfusion therapies and adjunctive pharmacological and non-pharmacological treatments are adopted in clinical practice and how their application can impact on patients' outcomes. Patients will be followed for 1 year after admission.
Conclusion:
The ESC ACCA-EAPCI EORP ACS STEMI registry is an international registry of care and outcomes of patients hospitalized with STEMI. It will provide insights into the contemporary patient profile, management patterns, and 1-year outcome of patients with STEMI.
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