Related Experiment Video
Updated: Jan 21, 2026

Human Neuroendocrine Tumor Cell Lines as a Three-Dimensional Model for the Study of Human Neuroendocrine Tumor Therapy
Published on: August 14, 2012
[Neuroendocrine tumors : Classification, clinical presentation and imaging]
H Scherübl1, F Raue2, K Frank-Raue2
1Klinik für Innere Medizin, Gastroenterologie, GI Onkologie und Infektiologie, Vivantes Klinikum Am Urban, Dieffenbachstraße 1, 10967, Berlin, Deutschland. hans.scheruebl@vivantes.de.
Context:
Neuroendocrine tumors (NET) are a heterogeneous group of neoplasms found in all organs. They often present with characteristic clinical syndromes due to hormone hypersecretion.
Diagnostics:
In addition to hormone diagnostics molecular-genetic work-up can play an important role.
Imaging:
Morphological imaging comprises ultrasound, endoscopy, computed tomography (CT) and magnetic resonance imaging (MRI) scans. Functional imaging of NET relies on radioligands that bind to specific receptors or transporters (Ga-68-DOTATATE-PET-CT, Tc-99-tektrotyd-SPECT/CT, F‑18-DOPA-PET/CT).
Therapy:
Somatostatin analogs either native or coupled to radionuclides are potent drugs for treating various neuroendocrine tumors.
Conclusion:
The requirements of imaging are determined by clinical presentation, laboratory findings, tumor stage, the presence of a tumor syndrome and the need of a personalized systemic treatment modality.
More Related Videos
Related Concept Videos
Self-Presentation: Self-Monitoring and Self-Handicapping
Self-Presentation
Strategies of Self-Presentation I: Strategic Self-Presentation
Processes of Self-Presentation
Strategies of Self-Presentation II: Self-Verification
Classification of Neurotransmitters

