Related Experiment Video
Updated: Jan 21, 2026

Genetic Manipulation in Δku80 Strains for Functional Genomic Analysis of Toxoplasma gondii
Published on: July 12, 2013
Comparative genomics and functional analysis of a highly adhesive dairy Lactobacillus paracasei subsp. paracasei
Anna Koryszewska-Bagińska1,2, Jan Gawor1, Adriana Nowak3
1Institute of Biochemistry and Biophysics, Polish Academy of Sciences (IBB PAS), Pawińskiego 5a, 02-106, Warsaw, Poland.
Abstract:
Various Lactobacillus paracasei strains are found in diverse environments, including dairy and plant materials and the intestinal tract of humans and animals, and are also used in the food industry or as probiotics. In this study, we have isolated a new strain L. paracasei subsp. paracasei IBB3423 from samples of raw cow milk collected in a citizen science project. IBB3423 showed some desired probiotic features such as high adhesion capacity and ability to metabolize inulin. Its complete genome sequence comprising the chromosome of 3,183,386 bp and two plasmids of 5986 bp and 51,211 bp was determined. In silico analysis revealed numerous genes encoding proteins involved in carbohydrate metabolism and of extracellular localization likely supporting interaction with host tissues. In vitro tests confirmed the high adhesion capacity of IBB3423 and showed that it even exceeds that of the highly adhesive L. rhamnosus GG. Curing of the larger plasmid indicated that the adhesive properties depend on the plasmid and thus could be determined by its pilus-encoding spaCBA genes.
More Related Videos
Related Concept Videos
Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes
Comparing the Survival Analysis of Two or More Groups
Three-Dimensional Analysis of Strain
Genomics
Cell Adhesion Molecules - Types and Functions
CAM Families
The Integrin family of proteins is primarily involved...
Adhesion
Capillary action is a result of water’s adhesive tendencies. When a narrow...

