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A Melanoma Patient-Derived Xenograft Model
Published on: May 20, 2019
Non-Melanoma Skin Cancers in the Older Patient
Ashley Albert1, Miriam A Knoll2, John A Conti3
1Department of Radiation Oncology, University of Mississippi Medical Center, 2500 N State St, Jackson, MS, 39216, USA.
Purpose Of Review:
The incidence of non-melanomatous skin cancer (NMSC) increases with age and there are specific considerations regarding management of NMSC for the older patient population. Here we will review current data regarding treatment considerations and options for older patients with NMSC.
Recent Findings:
Hypofractionated regimens and high-dose brachytherapy may be non-surgical treatment options for older patients with NMSC. Other less aggressive strategies such as active surveillance can also be considered in some settings. Management of NMSC in the older patient population requires a thorough assessment of comorbidities, frailty, and life expectancy. Additionally, discussions regarding goals of care and quality of life (QOL) issues are especially important in this population. Older patients with NMSC in particular may benefit from a tailored treatment plan based on current available data rather than a broad application of general treatment guidelines for NMSC.
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