Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Synthesis and Functions of Calcitonin00:51

Synthesis and Functions of Calcitonin

4.3K
Calcitonin, a vital polypeptide hormone, regulates calcium levels within body fluids. It is released by the parafollicular cells, also known as C cells, situated in the follicular epithelium of the thyroid gland. Calcitonin responds to fluctuations in blood calcium levels and the influence of gastrointestinal hormones like gastrin and cholecystokinin.
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...
4.3K
Functional Groups02:45

Functional Groups

87.8K
Functional groups are a group of atoms with characteristic properties, which when linked to the carbon skeleton of a molecule, alter the properties of that molecule. For example, the presence of certain functional groups on a molecule will make them hydrophilic, whereas others will make them hydrophobic. These functional groups are an indispensable part of organic chemistry and important components of biological molecules, such as carbohydrates, proteins, lipids, and nucleic acids. Each...
87.8K
Functional Groups02:45

Functional Groups

24.2K
24.2K
Molecular Orbital Theory I02:35

Molecular Orbital Theory I

47.1K
Overview of Molecular Orbital Theory
47.1K
Serum Studies: Renal Function Tests01:24

Serum Studies: Renal Function Tests

382
Renal function tests are crucial for assessing kidney health, monitoring disease progression, and evaluating the kidneys' efficiency in waste elimination, fluid balance, and electrolyte regulation. These tests offer critical insights into kidney function, even though routine measurements may appear normal until there is a significant decline in the glomerular filtration rate or GFR. Typically, signs of kidney impairment only become evident when the GFR falls to about 50% of its normal level.
382
Functionalism01:11

Functionalism

2.5K
William James, John Dewey, and Charles Sanders Peirce were instrumental in founding functional psychology, which draws heavily from Darwin's theory of evolution by natural selection. This theory suggests that individual traits, including behaviors, are adapted to their environments through natural selection. At the heart of functionalism is the concept of adaptation, meaning that a trait enhances an individual's chances of survival and reproduction.
James envisioned psychology's...
2.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction to "Multifunctional Chemosensors for the Simultaneous Detection of Copper and Mercury Ions: Applications in Test Strip Fabrication, Spiking Studies, and Logic Gate Formulation".

ACS omega·2025
Same author

Multifunctional Chemosensors for the Simultaneous Detection of Copper and Mercury Ions: Applications in Test Strip Fabrication, Spiking Studies, and Logic Gate Formulation.

ACS omega·2025
Same author

Chromogenic Chemosensor for Simultaneous Detection of PO<sub>4</sub> <sup>3-</sup> and CO<sub>3</sub> <sup>2-</sup> Anions in Organo-Aqueous Solutions: Application in Arduino Based Electronic Color Sensor Device and Logic Gate.

Chemphyschem : a European journal of chemical physics and physical chemistry·2024
Same author

Selective Chromogenic Chemosensors for Arsenite Anion: A Facile Approach to Analyzing Arsenite in Honey, Milk, and Water Samples.

ChemPlusChem·2024
Same author

Colorimetric differentiation of arsenite and arsenate anions using a bithiophene sensor with two binding sites: DFT studies and application in food and water samples.

Analytical methods : advancing methods and applications·2024
Same author

Pyrene-Oxadiazoles for Organic Light-Emitting Diodes: Triplet to Singlet Energy Transfer and Role of Hole-Injection/Hole-Blocking Materials.

The Journal of organic chemistry·2015

Related Experiment Video

Updated: Jan 21, 2026

Synthesis and Characterization of Functionalized Metal-organic Frameworks
11:27

Synthesis and Characterization of Functionalized Metal-organic Frameworks

Published on: September 5, 2014

49.1K

Functionalized pyrene-based AIEgens: synthesis, photophysical characterization and density functional theory studies.

Makesh Mohan1, Juliya James2, M N Satyanarayan1

  • 1Optoelectronics Laboratory, Department of Physics, National Institute of Technology Karnataka (NITK) Surathkal, Mangaluru, India.

Luminescence : the Journal of Biological and Chemical Luminescence
|July 31, 2019
PubMed
Summary

Three novel pyrene derivatives exhibit significant fluorescence, particularly P3 with cyanofunctionality, showing aggregation-induced emission. Their electronic properties were validated by experimental and theoretical density functional theory studies.

More Related Videos

Isolation and Characterization of Neutrophil-derived Microparticles for Functional Studies
06:56

Isolation and Characterization of Neutrophil-derived Microparticles for Functional Studies

Published on: March 2, 2018

10.8K
Synthesis, Functionalization, and Characterization of Fusogenic Porous Silicon Nanoparticles for Oligonucleotide Delivery
08:53

Synthesis, Functionalization, and Characterization of Fusogenic Porous Silicon Nanoparticles for Oligonucleotide Delivery

Published on: April 16, 2019

8.2K

Related Experiment Videos

Last Updated: Jan 21, 2026

Synthesis and Characterization of Functionalized Metal-organic Frameworks
11:27

Synthesis and Characterization of Functionalized Metal-organic Frameworks

Published on: September 5, 2014

49.1K
Isolation and Characterization of Neutrophil-derived Microparticles for Functional Studies
06:56

Isolation and Characterization of Neutrophil-derived Microparticles for Functional Studies

Published on: March 2, 2018

10.8K
Synthesis, Functionalization, and Characterization of Fusogenic Porous Silicon Nanoparticles for Oligonucleotide Delivery
08:53

Synthesis, Functionalization, and Characterization of Fusogenic Porous Silicon Nanoparticles for Oligonucleotide Delivery

Published on: April 16, 2019

8.2K

Area of Science:

  • Organic Chemistry
  • Materials Science
  • Spectroscopy

Background:

  • Pyrene derivatives are widely explored for their photophysical properties.
  • Developing new fluorescent materials with tunable emission is crucial for various applications.

Purpose of the Study:

  • To design, synthesize, and characterize novel pyrene-based derivatives (P1-P3) with substituted pyrazole moieties.
  • To investigate their photophysical properties, including aggregation-induced emission (AIE).
  • To correlate molecular structure with experimental and theoretical electronic properties.

Main Methods:

  • Synthesis and characterization of pyrene derivatives using standard spectroscopic techniques.
  • Ultraviolet-visible (UV-vis) and photoluminescence (PL) spectroscopy.
  • Fluorescence quantum yield measurements and ratiometric studies.
  • Cyclic voltammetry and Density Functional Theory (DFT) calculations.

Main Results:

  • Synthesized P1, P2, and P3 exhibited bathochromic shifts in UV-vis spectra with varying solvent polarity.
  • Significant fluorescence emission was observed in polar solvents (MeOH, DMF).
  • P3 showed a high fluorescence quantum yield (0.36%) due to cyanofunctionality.
  • Aggregation-induced emission (AIE) was confirmed by ratiometric studies in THF/H2O mixtures.
  • Experimental band gaps ranged from 2.26 to 2.31 eV.
  • DFT calculations correlated well with experimental HOMO, LUMO, and band gap values.

Conclusions:

  • The designed pyrene derivatives possess promising photophysical properties, including AIE.
  • The cyanofunctionality in P3 enhances fluorescence emission.
  • Experimental and theoretical studies confirm the structure-property relationships.