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Histone demethylase PHF2 activates CREB and promotes memory consolidation

Hye-Jin Kim1,2, Sung Won Hur1, Jun Bum Park1

  • 1Department of Physiology and Biomedical Science, Seoul National University College of Medicine, Seoul, Korea.

EMBO Reports
|July 31, 2019
PubMed
Summary

The plant homeodomain finger protein 2 (PHF2) enhances memory formation by epigenetically regulating memory genes. This histone demethylase is crucial for learning and memory consolidation.

Keywords:
CREBPHF2hippocampuslearning and memorylysine methylation

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