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Updated: Jan 21, 2026

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
Published on: June 6, 2025
Marked deterioration in rheumatoid arthritis associated bronchiectasis following treatment with Rituximab
K Musameh1, C D Campbell1, R M Rutherford1
1Department of Respiratory Medicine, University Hospital Galway, Galway, Ireland.
Abstract:
We report a 67 year old lady with Rheumatoid Arthritis (RA) and mild bronchiectasis (BE) whose treatment was escalated to Rituximab. Nine months after commencing Rituximab her lung sepsis worsened dramatically with repeated hospitalization, new sputum isolation of Stenotrophomonas maltophilia and Pseudomonas aeruginosa and marked radiological deterioration in BE. She was found to have a low serum IgG and IgM levels almost certainly as a complication of Rituximab. Immunoglobulin replacement therapy was instituted and her clinical status has slowly improved.
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