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Regional chromosomal localisation of APOA2 to 1q21-1q23
H R Middleton-Price1, J A van den Berghe, J Scott
1Mothercare Department of Paediatric Genetics, Institute of Child Health, London, UK.
Human Genetics
|July 1, 1988
Abstract:
Using in situ hybridisation, we have mapped APOA2 to the 1q21-1q23 region of chromosome 1. DNA hybridisation to somatic cell hybrids made from cells carrying a balanced translocation between X and 1 confirms the localisation as proximal to 1q23. This was further confirmed by the presence of two polymorphic alleles in a cell line carrying a deletion of 1q25-1q32.