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Mild and Practical Dirhodium(II)/NHPI-Mediated Allylic and Benzylic Oxidations with Air as the Oxidant
Yi Wang1, Xiaochuan Chen1, Hong Jin2
1Key Laboratory of Green Chemistry & Technology of Ministry of, Education, College of Chemistry, Sichuan University, Chengdu, 610064, P.R. China.
Abstract:
Aerobic allylic and benzylic oxidations catalyzed by dirhodium(II) complexes with N-hydroxyphthalimide (NHPI) are described. The open flask reaction occurs at mild temperature, using air as the oxidant. Mechanistic studies suggest that dirhodium(II) complexes axially coordinate with NHPI to activate the O-H bond in NHPI and decrease the bond-dissociation energy (BDE).
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