Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

262
Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
262
Theory of Romantic Attachment in Adulthood03:34

Theory of Romantic Attachment in Adulthood

48.6K
Attachment is a long-standing connection or bond with others. While Attachment Theory was conceived in developmental psychology to describe infant-caregiver bonding, it's been extended into adulthood to include romantic relationships. 
48.6K
The Availability Heuristic01:08

The Availability Heuristic

6.9K
A heuristic is a general problem-solving framework (Tversky & Kahneman, 1974). You can think of these as mental shortcuts that are used to solve problems. Different types of heuristics are used in different types of situations, and the impulse to use a heuristic occurs when one of five conditions is met (Pratkanis, 1989):
6.9K
Noble Gases02:54

Noble Gases

22.5K

The elements in group 18 are noble gases (helium, neon, argon, krypton, xenon, and radon). They earned the name “noble” because they were assumed to be nonreactive since they have filled valence shells. In 1962, Dr. Neil Bartlett at the University of British Columbia proved this assumption to be false.
22.5K
Measuring Reaction Rates03:09

Measuring Reaction Rates

28.7K
Polarimetry finds application in chemical kinetics to measure the concentration and reaction kinetics of optically active substances during a chemical reaction. Optically active substances have the capability of rotating the plane of polarization of linearly polarized light passing through them—a feature called optical rotation. Optical activity is attributed to the molecular structure of substances. Normal monochromatic light is unpolarized and possesses oscillations of the electrical...
28.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Extra-intestinal manifestations associated with Crohn's disease].

Nederlands tijdschrift voor geneeskunde·2024
Same author

Circulating Iron in Patients with Sickle Cell Disease Mediates the Release of Neutrophil Extracellular Traps.

Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie·2023
Same author

Long-term efficacy of clinical hunger provocation to wean feeding tube dependent children.

Clinical nutrition (Edinburgh, Scotland)·2020
Same author

Intranasal treatment of vitamin B<sub>12</sub> deficiency in children.

European journal of pediatrics·2019
Same author

Outcome of initially nonoperative treatment for acute simple appendicitis in children.

Journal of pediatric surgery·2018
Same author

Inflammatory and endothelial markers during vaso-occlusive crisis and acute chest syndrome in sickle cell disease.

American journal of hematology·2017

Related Experiment Video

Updated: Jan 21, 2026

P50 Sensory Gating in Infants
12:55

P50 Sensory Gating in Infants

Published on: December 26, 2013

9.6K

[An infant with prolonged jaundice].

Marein Schimmel1,2, C M Frank Kneepkens3, Tim J G de Meij3

  • 1Amsterdam UMC, afd. Kindergeneeskunde, Amsterdam.

Nederlands Tijdschrift Voor Geneeskunde
|July 31, 2019
PubMed
Summary
This summary is machine-generated.

Prolonged jaundice beyond 21 days in newborns requires investigation for neonatal cholestasis. Pale stools are a critical sign, necessitating immediate further testing, especially in infants with darker skin tones.

More Related Videos

Author Spotlight: Marmoset Research - Scope and Challenges
04:52

Author Spotlight: Marmoset Research - Scope and Challenges

Published on: June 9, 2023

2.6K
Infant Auditory Processing and Event-related Brain Oscillations
06:34

Infant Auditory Processing and Event-related Brain Oscillations

Published on: July 1, 2015

16.9K

Related Experiment Videos

Last Updated: Jan 21, 2026

P50 Sensory Gating in Infants
12:55

P50 Sensory Gating in Infants

Published on: December 26, 2013

9.6K
Author Spotlight: Marmoset Research - Scope and Challenges
04:52

Author Spotlight: Marmoset Research - Scope and Challenges

Published on: June 9, 2023

2.6K
Infant Auditory Processing and Event-related Brain Oscillations
06:34

Infant Auditory Processing and Event-related Brain Oscillations

Published on: July 1, 2015

16.9K

Area of Science:

  • Neonatology
  • Pediatric Gastroenterology
  • Hepatology

Background:

  • Neonatal cholestasis is a serious condition requiring prompt evaluation.
  • Prolonged jaundice, persisting beyond 21 days, warrants exclusion of neonatal cholestasis, irrespective of feeding method.
  • Pale stools serve as a critical alarm symptom for neonatal cholestasis.

Observation:

  • A case study of a five-week-old infant with conjugated hyperbilirubinemia is presented.
  • Jaundice was initially unrecognized due to the infant's dark skin, despite yellow scleras.
  • The infant presented with pale stools, confirmed by a stool color card.

Findings:

  • Liver biopsy confirmed biliary atresia as the diagnosis.
  • The infant underwent a Kasai hepatoportoenterostomy for treatment.
  • Delayed recognition of jaundice in infants with dark skin highlights diagnostic challenges.

Implications:

  • Neonatal cholestasis is always pathological and necessitates thorough investigation.
  • Scleral inspection is crucial for jaundice detection in infants with dark skin.
  • Early identification and intervention are vital for managing neonatal cholestasis and biliary atresia.