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Updated: Jan 21, 2026

Luminophore Formation in Various Conformations of Bovine Serum Albumin by Binding of GoldIII
Published on: August 31, 2018
Structural Characterization of a Gold/Serum Albumin Complex
Alessandro Pratesi1, Damiano Cirri1, Dolores Fregona2
1Laboratory of Metals in Medicine (MetMed), Department of Chemistry "U. Schiff" , University of Florence , via della Lastruccia 3 , 50019 Sesto Fiorentino , Italy.
Abstract:
The medicinal gold(III) dithiocarbamato complex AuL12 forms a stable adduct with bovine serum albumin. The crystal structure reveals that a single gold(I) center is bound to Cys34, with the dithiocarbamato ligand being released. To the best of our knowledge, this is the first structure for a gold adduct of serum albumin.
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