Related Experiment Video

Updated: Jan 21, 2026

Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents
09:28

Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents

Published on: September 16, 2020

9.3K

Retinopathy of prematurity in Rwanda: a prospective multi-centre study following introduction of screening and

Francis Mutangana1, Charles Muhizi2, Godelieve Mudereva3

  • 1Ophthalmology, King Faisal Hospital, Kigali, Rwanda.

Eye (London, England)
|August 1, 2019
PubMed

Insights

Risk factors for retinopathy of prematurity (ROP) in Rwanda include prolonged oxygen use and hyperglycemia. These findings highlight the need for improved neonatal care and adjusted screening guidelines to address this emerging health issue.

Area of Science:

  • Neonatal ophthalmology
  • Public health
  • Perinatal medicine

Background:

  • Retinopathy of prematurity (ROP) is a significant cause of visual impairment in premature infants.
  • Established ROP screening programs are crucial for early detection and intervention.
  • The epidemiology and risk factors for ROP in African populations require further investigation.

Purpose of the Study:

  • To identify risk factors associated with retinopathy of prematurity (ROP) in a newly established screening and management program in Rwanda.
  • To evaluate the incidence of ROP and treatment-warranted ROP within this specific population.
  • To inform the development of targeted interventions and improved neonatal care practices.

Main Methods:

  • A multi-center prospective study involving 795 eligible infants (gestational age < 35 weeks or birth weight < 1800g).
  • ROP screening was conducted on 424 infants, with classification based on the revised International Classification of ROP (2005).
  • Maternal and perinatal risk factors were collected from neonatal records, with univariate and multivariate analyses performed.

Main Results:

  • Any ROP developed in 7.3% of screened infants, with 41.9% requiring treatment.
  • Significant risk factors identified in univariate analysis included increased supplemental oxygen duration, low gestational age, low birth weight, hyperglycemia, blood transfusion, and sepsis.
  • Multivariate analysis confirmed longer exposure to supplemental oxygen and hyperglycemia as significant independent risk factors for ROP.

Conclusions:

  • Retinopathy of prematurity (ROP) is an emerging health concern in Rwanda, necessitating dedicated screening and treatment programs.
  • Current ROP screening guidelines may need to be adapted for the Rwandan context, potentially screening infants beyond the 2013 American Academy guidelines.
  • Enhancing the quality of neonatal care, particularly in oxygen administration and monitoring, is critical to reduce the incidence and severity of ROP.
Abstract

More Related Videos

Tear-Derived Exosomal miR-15a as New Diagnostic Tool for Diabetic Retinopathy07:45

Tear-Derived Exosomal miR-15a as New Diagnostic Tool for Diabetic Retinopathy

Published on: December 30, 2025

294
Application of Optical Coherence Tomography to a Mouse Model of Retinopathy08:22

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

5.2K

Related Concept Videos

Primary Healthcare Services01:30

Primary Healthcare Services

Primary care promotes wellness and prevents disease. This care includes health promotion, education, protection (such as immunizations), early disease screening, and environmental considerations. Settings providing this type of healthcare include physician offices, public health clinics, school nursing, and community health nursing.
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
2.0K
Preventive Healthcare Services01:30

Preventive Healthcare Services

Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
1.9K
Multi-input and Multi-variable systems01:22

Multi-input and Multi-variable systems

Cruise control systems in cars are designed as multi-input systems to maintain a driver's desired speed while compensating for external disturbances such as changes in terrain. The block diagram for a cruise control system typically includes two main inputs: the desired speed set by the driver and any external disturbances, such as the incline of the road. By adjusting the engine throttle, the system maintains the vehicle's speed as close to the desired value as possible.
In the absence of...
401
Introduction to R01:11

Introduction to R

R is a powerful software environment for statistical computing and graphics. Originating as an implementation of the S language, developed at Bell Laboratories, R has evolved into a robust, open-source statistical software favored by statisticians and data scientists worldwide. Its comprehensive suite includes data manipulation, calculation, and graphical display capabilities, making it versatile for data analysis and visualization. Its programming language is at the core of R's...
4.3K
Introduction to Virus01:28

Introduction to Virus

Viruses are unique biological entities that blur the boundary between living and non-living systems. Although they lack cellular structure and metabolic processes, they can exhibit characteristics of life when infecting a host. Their defining feature is a nucleic acid core, composed of either DNA or RNA, encapsulated within a protein coat called a capsid. This simple structure allows them to invade host cells and use their machinery for replication efficiently.Viral Structure and...
1.3K
Introduction to Functional Groups02:08

Introduction to Functional Groups


Functional groups are group of atoms with specific chemical properties that occur within organic molecules and sometimes denoted as “R”. Functional groups are found along the carbon backbone of macromolecules can form chains or rings of carbon atoms. Functional groups can “functionalize” a compound by enabling it to adopt different physical and chemical properties.  
Types of common functional groups
The table below summarizes some of the major functional groups in organic chemistry....
34.9K