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Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
Published on: April 11, 2018
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Biopsy Path Contamination in Primary Bone Sarcomas.
Jairo Greco Garcia1, Dayane Screpante Marques2, Dan Carai Maia Viola1
1Setor de Ortopedia Oncológica da Disciplina de Ortopedia, Departamento de Ortopedia e Traumatologia, Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil.
Revista Brasileira De Ortopedia
|August 1, 2019
Summary
Bone biopsy pathway contamination is rare in primary bone sarcoma patients. Specialized centers ensure the safety of this procedure, minimizing risks for patients undergoing oncologic treatment.
Area of Science:
- Oncology
- Orthopedic Surgery
- Pathology
Background:
- Bone biopsies are crucial for diagnosing primary bone sarcomas.
- Concerns exist regarding potential neoplastic cell seeding along the biopsy tract.
- Minimizing contamination is vital for successful treatment outcomes.
Purpose of the Study:
- To assess the incidence of biopsy pathway contamination in primary bone sarcoma patients.
- To identify clinical factors associated with biopsy tract seeding.
Main Methods:
- Retrospective review of anatomopathological reports.
- Evaluation of patients treated at an Orthopedic Oncology Sector.
- Analysis of 148 patient cases.
Main Results:
- Only 1 out of 148 patients (0.68%) showed neoplastic cell contamination in the biopsy pathway.
- The overall incidence of contamination was exceptionally low.
Conclusions:
- Bone biopsy is a safe procedure for primary bone sarcoma patients when performed in specialized centers.
- Expertise in specialized orthopedic oncology settings significantly reduces the risk of biopsy pathway contamination.
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