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Loperamide Overdose.

Casey Arnold¹, Carmen J Martinez Martinez¹

¹Emergency Medicine, Advent Health Florida Hospital, Orlando, USA.

|August 1, 2019

Summary

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Loperamide overdose can cause life-threatening cardiac issues, including arrhythmias, especially in patients with long QT syndrome. Emergency physicians must recognize these risks due to increasing overdose cases.

Area of Science:

Cardiology
Emergency Medicine
Clinical Toxicology

Background:

The opioid epidemic has led to increased loperamide misuse.
Loperamide overdose presents significant cardiac risks, necessitating emergency department (ED) awareness.

Observation:

A 35-year-old male with long QT syndrome experienced severe arrhythmias and electrolyte disturbances after a loperamide overdose.
The patient required multiple defibrillator shocks due to the overdose complications.

Findings:

Loperamide overdose can precipitate life-threatening cardiac arrhythmias.
Underlying conditions like long QT syndrome exacerbate cardiac risks from loperamide.

Implications:

Emergency physicians need heightened awareness of loperamide overdose presentations.

Keywords:

imodium® overdose long qt syndrome loperamide overdose opioid torsades

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Prompt recognition and management are crucial for mitigating severe cardiac events in loperamide toxicity.