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Updated: Jan 21, 2026

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Published on: November 11, 2025
Video interpretation and diagnosis of pediatric amblyopia and eye disease
Kourosh Sabri1,2,3, Prima Moinul1, Nasrin Tehrani4
1Department of Surgery, Division of Ophthalmology, McMaster University, Canada.
Insights
Video screening shows potential for interpreting paediatric eye exams. While direct assessment showed high agreement, video interpretation varied, indicating a need for further research into its accuracy for diagnosing childhood eye conditions.
Area of Science:
- Ophthalmology
- Medical Imaging
- Paediatric Healthcare
Background:
- Paediatric eye examinations require accurate interpretation.
- Video screening offers a potential alternative method for assessment.
Purpose of the Study:
- To evaluate the utility of video screening for interpreting paediatric eye examination results.
- To compare agreement levels between direct clinical assessment and video interpretation.
Main Methods:
- Prospective, multi-centred, blinded study involving children aged 5 months to 11 years.
- Phase 1: Three examiners assessed children directly. Phase 2: Two examiners interpreted video recordings of examinations.
- Agreement measured using Gwet's AC1, assessing lid function, pupillary function, ocular motility, strabismus, nystagmus, torticollis, and facial asymmetry.
Main Results:
- Phase 1 achieved ≥84% agreement for most assessments (except heterotropia).
- Phase 2 showed agreement ranging from 55-100% between direct examination and video interpretation.
- Variability in agreement was observed when interpreting video findings compared to direct assessment.
Conclusions:
- Video-recorded screening may be useful for assessing children's eyes, particularly with experienced clinicians.
- Further research is needed to determine the accuracy of ophthalmologists interpreting video recordings of eye exams.
- The study highlights the potential but also the limitations of video screening in paediatric ophthalmology.
Aim:
The aim of this study was to assess the potential of using video screening to interpret the results of paediatric eye examinations.
Design:
Prospective multi-centred, blinded study.
Methods:
Children aged 5 months to 11 years referred to a paediatric ophthalmology centre were enrolled in the study. Outcome measures included the degree of agreement between examiners for assessment of various aspects of paediatric eye examination. In Phase 1, children were individually assessed in the clinic by three different examiners to determine the level of agreement. In Phase 2 a video recording was made of the first ophthalmologist examining the children. The other two examiners viewed the video recordings to make their diagnoses. Areas of assessment included lid function, pupillary function, ocular motility, strabismus, nystagmus, torticollis and facial asymmetry. Agreement between examiners was measured using Gwet's agreement coefficient (AC1).
Results:
A total of 27 patients in Phase 1 (mean age 4.0 years) and 160 children in Phase 2 (mean age 4.8 years) underwent clinical and video-recorded screening. In Phase 1, all but one area of ocular examination (heterotropia) achieved ≥84% agreement between three examiners. In Phase 2, there was greater variation between direct clinical examination and interpretation of video findings, ranging from 55-100% agreement.
Conclusion:
Using experienced clinicians and changing only one variable in Phase 2 (the method of assessment - direct examination versus video interpretation), the results show the possible usefulness of video-recorded screening as a means of assessing children. Further research is indicated to assess the accuracy of ophthalmologists interpreting video recordings of eye examinations performed by trained non-eye-care professionals.
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