Related Experiment Video
Updated: Jan 21, 2026
06:50
A Model of Acute Lung Injury Following Visceral Ischemia-Reperfusion by Supra-Coeliac Aortic Cross Clamping in Rats
Published on: August 15, 2025
378
Determining whether coeliac disease case-finding in primary care is better than random testing: a retrospective study
1Associate Specialist, Department of Gastroenterology, York Teaching Hospital NHS Foundation Trust, York, UK.
BJGP Open
|August 2, 2019
Summary
Case-finding for coeliac disease in primary care is no more effective than random population testing. Improved education on coeliac disease indications is necessary for both the public and physicians.
Area of Science:
- Gastroenterology
- Public Health
- Diagnostic Medicine
Background:
- Over 75% of coeliac disease patients in the UK remain undiagnosed, representing a significant public health challenge.
- Undiagnosed coeliac disease can lead to serious long-term health complications.
Purpose of the Study:
- To evaluate the effectiveness of case-finding strategies for coeliac disease in primary care settings.
- To compare case-finding with random testing for identifying coeliac disease.
Main Methods:
- A pragmatic study analyzed coeliac serology testing referrals and indications across 38 GP practices over 12 months.
- Follow-up data was collected for 12 months to track positive serology conversion to duodenal biopsy.
Main Results:
- Case-finding for coeliac disease in primary care demonstrated no significant advantage over random population testing.
- Only 71% of individuals with positive coeliac serology proceeded to a duodenal biopsy within the subsequent year.
Conclusions:
- Enhanced education for the public and primary care physicians regarding coeliac disease diagnostic indications is crucial.
- Primary care settings may not be the optimal environment for effective coeliac disease case-finding.
Related Concept Videos
01:27Coronary Artery Disease V: Interprofessional Care
220
Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
220
01:20Bioequivalence Experimental Study Designs: Completely Randomized and Randomized Block Designs
241
Body:Bioequivalence experimental study designs are crucial methodologies used in evaluating and comparing the bioavailability of different drug products. These designs are categorized into various types: completely randomized, randomized block, repeated measures, cross and carry-over, and Latin square designs.Completely randomized designs involve randomly allocating treatments to all subjects participating in the experiment. This allocation is achieved by assigning unique random numbers to...
241
01:28Chronic Kidney Disease III: Interprofessional Care
359
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
359
01:27Peripheral Artery Disease III: Interprofessional Care
268
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
268
01:25Peptic Ulcer Disease V: Surgical Management and Nursing Care
847
Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
Surgical Interventions for Peptic Ulcer Disease
847
01:03Finding the Center of Gravity
4.3K
The center of gravity of a body is an imaginary point where the body's total weight is assumed to be concentrated, and the body is perfectly balanced. The center of the mass of a body is a point at which the whole of the mass of the body appears to be concentrated. If the acceleration due to gravity, g, has the same value at all points on a body, its center of gravity is identical to its center of mass. The center of gravity of homogeneous bodies such as a sphere, cube, or rectangular plate...
4.3K