Giant low-grade appendiceal mucinous neoplasm: A case report

Area of Science:

• Gastroenterology
• Surgical Oncology

Background:

• Appendiceal mucinous neoplasm (AMN) is a rare gastrointestinal tumor.
• AMN often presents with non-specific symptoms, leading to diagnostic challenges and potential misdiagnosis.

Observation:

• A 63-year-old woman presented with a right lower abdominal mass.
• Laparotomy revealed an appendiceal mucocele, treated with appendectomy.
• Histological examination confirmed low-grade appendiceal mucinous neoplasm (LAMN) with no lymph node metastasis or positive surgical margins.

Findings:

• The patient received six cycles of adjuvant chemotherapy post-surgery.
• The patient has remained disease-free for over a year following treatment.
• This case demonstrates a favorable outcome for LAMN managed with surgery and chemotherapy.

Implications:

• Standardized pathological diagnosis is essential for selecting optimal surgical strategies for LAMN.
• Detailed tumor documentation in surgical records aids in post-operative follow-up.
• Multidisciplinary approaches involving pathology and surgery are key in managing rare appendiceal neoplasms.