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Updated: Jan 21, 2026
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Systemic Bacterial Infection and Immune Defense Phenotypes in Drosophila Melanogaster
Published on: May 13, 2015
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Study of dCTCF Insulator Activity in Drosophilamelanogaster Model Systems
N E Postika1, T A Ivlieva2, P G Georgiev2
1Institute of Gene Biology, Russian Academy of Sciences, 119334, Moscow, Russia. nk.postika@gmail.com.
Doklady. Biochemistry and Biophysics
|August 2, 2019
Abstract:
Using transgenic Drosophila model systems, we showed that four binding sites for the architectural protein dCTCF per se cannot form an effective insulator that blocks enhancers and protects against the Polycomb-dependent repression. These results suggest that, in the known Drosophila insulators, the dCTCF protein functions in cooperation with other architectural proteins.
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