Related Experiment Video
Updated: Jan 21, 2026
26:41
Perspectives on Neuroscience
Published on: July 31, 2007
5.3K
Ductus arteriosus-associated infective endarteritis: Lessons from the past, future perspective
Alessia Callegari1, Barbara Burkhardt1, Christa Relly2
1Pediatric Cardiology, Department of Surgery, Pediatric Heart Center, University Children's Hospital Zurich, Zurich, Switzerland.
Congenital Heart Disease
|August 2, 2019
Summary
Patent ductus arteriosus infective endarteritis (PDA-IE) is a rare but serious condition. Early diagnosis and antibiotic treatment are crucial for recovery, even after PDA closure.
Area of Science:
- Pediatric Cardiology
- Infectious Diseases
- Neonatology
Background:
- Patent ductus arteriosus (PDA) closure is routine, yet PDA-associated infective endarteritis (PDA-IE) remains a rare complication.
- PDA-IE can occur during ductus arteriosus patency or shortly after its obliteration, necessitating clinical vigilance for unexplained fever.
Observation:
- A 7-week-old infant with Staphylococcus aureus sepsis presented with a new heart murmur.
- Transthoracic echocardiography revealed PDA-IE at the pulmonary artery end of an obliterated PDA.
Findings:
- Successful antibiotic treatment led to vegetation reduction and complete infant recovery.
- Literature review confirmed PDA-IE as a rare, life-threatening condition in neonates and infants, even post-closure.
Implications:
- Transthoracic echocardiography is valuable in diagnosing PDA-IE in septic neonates with bacteremia, especially with fever of unknown origin or new heart murmurs.
- Clinicians must maintain a high index of suspicion for PDA-IE in infants presenting with sepsis and cardiac findings.
Related Concept Videos
01:27Psychodynamic Perspectives on Personality
1.5K
The psychodynamic perspective in psychology asserts that most personality functions operate unconsciously, outside of awareness. This means that the motives and emotions driving behavior often remain hidden, automatically buried in the unconscious mind as a defense mechanism to shield us from psychological distress. According to this theory, the unconscious mind contains thoughts, memories, and emotions that are too disturbing to face directly.
Psychodynamic theorists argue that unconscious...
Psychodynamic theorists argue that unconscious...
1.5K
01:19The Behavioral Perspective on Personality
804
Behaviorists view personality as primarily shaped by environmental reinforcements and consequences. According to this perspective, behavior is influenced by external stimuli, and individuals adjust their actions based on rewards and punishments. Over time, learning histories — accumulated patterns of reinforcement — play a significant role in shaping personality. Behaviors that lead to positive outcomes are reinforced, while those resulting in negative outcomes are diminished.
804
01:23Criticisms of the Evolutionary Perspective
346
In a study where individuals posing as strangers offered compliments and proposed casual sex to students, the responses differed significantly based on gender. Not a single woman accepted the proposal, while 70% of the men agreed. This outcome provides a useful scenario to explore through the lens of evolutionary psychology and social learning theory, highlighting the diverse perspectives on human sexual behaviors.
Evolutionary psychology provides one explanation for these findings, suggesting...
Evolutionary psychology provides one explanation for these findings, suggesting...
346
01:30Social Cognitive Perspective on Personality
994
Social cognitive perspectives on personality emphasize the importance of conscious awareness, beliefs, expectations, and goals in shaping behavior. These perspectives incorporate behaviorist principles, such as learning through reinforcement and conditioning, but extend beyond them by highlighting human reasoning and planning. Unlike traditional behaviorist views, social cognitive theory focuses on how individuals reflect on their past experiences and plan for future outcomes by considering...
994
01:14Changes in Skin Color: Clinical Perspectives
3.3K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
3.3K
01:23Carl Rogers' Humanistic Perspective on Personality
1.9K
Carl Rogers, a key figure in humanistic psychology, believed that individuals possess an innate potential for growth and fulfillment. According to his model of personality, three significant components define an individual: the organism, the self, and conditions of worth.
The organism refers to an individual's inherent blueprint, which Rogers saw as innately positive and directed toward helping others, unlike Freud's view of the id as driven by base impulses. The self is a person's...
The organism refers to an individual's inherent blueprint, which Rogers saw as innately positive and directed toward helping others, unlike Freud's view of the id as driven by base impulses. The self is a person's...
1.9K