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Updated: Jan 21, 2026

Functional Imaging with Reinforcement, Eyetracking, and Physiological Monitoring
Published on: November 13, 2008
Detecting Delirium Using a Physiologic Monitor
Malissa A Mulkey1, Daniel Erik Everhart, Sunghan Kim
1Malissa A. Mulkey, MSN, APRN, CCNS, CCRN, CNRN, is a neuroscience clinical nurse specialist at Duke University Hospital, Durham, North Carolina; and PhD candidate at East Carolina University, Greenville, North Carolina. Daniel Erik Everhart, PhD, ABPP, is a professor at East Carolina University, Greenville, North Carolina. Sunghan Kim, PhD, is from East Carolina University, Greenville, North Carolina. DaiWai M. Olson, PhD, RN, CCRN, FNCS, is a professor at the University of Texas Southwestern, Dallas. Sonya R. Hardin, PhD, CCRN, ACNS-BC, NP-C, is a dean and professor at University of Louisville, Kentucky.
Delirium is often missed, but electroencephalogram (EEG) monitoring shows promise for earlier detection. This objective method could improve patient outcomes by identifying neuroelectrical changes before behavioral symptoms appear.
Area of Science:
- Neuroscience
- Critical Care Medicine
- Geriatrics
Background:
- Delirium affects up to 20% of acute care and 80% of critically ill patients annually.
- Current diagnostic methods rely on behavioral symptoms, leading to missed diagnoses in approximately 80% of cases.
- The economic burden of delirium in the US is estimated at $164 million annually.
Purpose of the Study:
- To evaluate the utility of electroencephalogram (EEG) monitoring for early and accurate delirium detection.
- To explore the potential of newer, cost-effective EEG technologies for routine clinical use.
Main Methods:
- Review of the established utility of conventional electroencephalogram (EEG) in delirium diagnosis.
- Discussion of neurochemical and neuroelectrical changes preceding behavioral symptoms.
- Exploration of newer, limited-lead EEG technology with automatic processing capabilities.
Main Results:
- Neuroelectrical changes associated with delirium occur before behavioral symptoms, making EEG a potential tool for early identification.
- Integrating EEG analysis with clinical assessment significantly enhances delirium detection accuracy.
- Newer EEG technologies may reduce costs and the need for expert interpretation, making it more accessible.
Conclusions:
- EEG monitoring offers an objective method for earlier delirium recognition, potentially before symptom onset.
- Implementing accessible EEG technology could improve nursing interventions and reduce long-term patient consequences.
- Objective EEG assessment could revolutionize delirium care and establish a new standard of care.
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