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Pertussis in the Association of Southeast Asian Nations: epidemiology and challenges
Usa Thisyakorn1, Terapong Tantawichien2, Chule Thisyakorn1
1Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Insights
Pertussis, a dangerous respiratory illness, is resurging globally. This review examines pertussis epidemiology and control in Southeast Asia, recommending enhanced surveillance and research.
Area of Science:
- Public Health
- Infectious Diseases
- Epidemiology
Background:
- Pertussis (whooping cough) is a highly contagious respiratory illness caused by Bordetella pertussis.
- Infants and young children face severe risks, and older individuals can transmit the disease to unprotected infants.
- Pertussis control has faltered in some highly vaccinated nations, leading to increased incidence and global concern.
Purpose of the Study:
- To review pertussis surveillance systems, control measures, and epidemiologic trends in Southeast Asia.
- To highlight the limited attention given to pertussis epidemiology in this region.
- To provide recommendations for improving pertussis surveillance and research in Southeast Asia.
Main Methods:
- This study employed a narrative review methodology.
- Literature search focused on pertussis surveillance, control, epidemiology, and research in Southeast Asia.
- Data synthesis and analysis of regional trends and research gaps were performed.
Main Results:
- Pertussis surveillance systems and control measures vary across Southeast Asia.
- Epidemiologic trends indicate a resurgence in some areas, yet comprehensive data is lacking.
- Region-specific pertussis research is limited, hindering effective control strategies.
Conclusions:
- There is a critical need to strengthen pertussis surveillance and research in Southeast Asia.
- Implementing enhanced national immunization programs and surveillance is crucial for controlling pertussis outbreaks.
- Further research is essential to understand and combat the resurgence of pertussis in the region.
Abstract:
Pertussis is a highly infectious respiratory disease caused by Bordetella pertussis. Infants and young children are particularly at risk of severe and life-threatening disease. Infectious older individuals may transmit Bordetella pertussis to unprotected infants. Pertussis control measures have even failed in some countries with high pertussis vaccination coverage rates, leading to increased incidence rates. In 2014, this caused the World Health Organization to declare pertussis resurgent in some countries and led to recommendations regarding pertussis surveillance and national immunization programs. Despite the resurgence of pertussis, epidemiology of the disease in Southeast Asia has received little attention. In this narrative review, we describe pertussis surveillance systems, control measures, epidemiologic trends, and region-specific pertussis research in Southeast Asia. We also make recommendations for the intensification of pertussis surveillance and research in the region.
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