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Published on: August 30, 2020
Subarachnoid neurocysticercosis and an intracranial infectious aneurysm: case report
Abstract:
Infectious intracranial aneurysms (IIAs) represent 2%-6% of all intracranial aneurysms and, classically, have been associated with bacterial or fungal agents. The authors report the case of a 42-year-old woman who presented with a typical history of subarachnoid hemorrhage. Digital subtraction angiography (DSA) showed an aneurysmal dilatation on the frontal M2 segment of the left middle cerebral artery (MCA). The patient was treated surgically, and multiple cysts were found in the left carotid and sylvian cisterns, associated with a dense inflammatory exudate that involved the MCA. The cysts were removed, and a fusiform aneurysmal dilatation was identified. The lesion was not amenable to direct clipping, so the authors wrapped it. Histopathological analysis of the removed cysts revealed the typical pattern of subarachnoid neurocysticercosis. The patient received cysticidal therapy with albendazole and corticosteroids, and she recovered uneventfully. Follow-up DSA performed 6 months after surgery showed complete resolution of the aneurysm. The authors performed a review of the literature and believe that there is sufficient evidence to affirm that the subarachnoid form of neurocysticercosis may lead to the development of an IIA and that Taenia solium should be listed among the possible etiological agents of IIAs, along with bacterial and fungal agents.
Insights
Neurocysticercosis, a parasitic infection, can cause infectious intracranial aneurysms (IIAs). This case demonstrates that subarachnoid neurocysticercosis can lead to IIAs, suggesting Taenia solium as an etiological agent.
Area of Science:
- Neurology
- Infectious Diseases
- Radiology
Background:
- Infectious intracranial aneurysms (IIAs) are rare, typically caused by bacterial or fungal infections.
- Subarachnoid hemorrhage is a common presentation of IIAs.
Observation:
- A 42-year-old woman presented with subarachnoid hemorrhage, revealing an aneurysm on the left middle cerebral artery (MCA).
- Surgical exploration identified cysts and inflammatory exudate involving the MCA, with histopathology confirming neurocysticercosis.
Findings:
- Subarachnoid neurocysticercosis was identified as the cause of the infectious intracranial aneurysm.
- The aneurysm resolved completely after surgical management and cysticidal therapy with albendazole.
Implications:
- This case suggests that Taenia solium, the causative agent of neurocysticercosis, should be considered an etiological agent for IIAs.
- Expanding the differential diagnosis for IIAs to include parasitic infections like neurocysticercosis is crucial for appropriate management.
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