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Syringe infusion pump with absolute piston displacement control.

Jian Wern Ong1, Dwayne Chung Kim Chung1, Eric Shen Lin1

  • 1Laboratory for Optics and Applied Mechanics, Department of Mechanical and Aerospace Engineering, Monash University, Clayton VIC3800, Australia.

The Review of Scientific Instruments
|August 3, 2019
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Summary

This study introduces a linear servo actuator for syringe pumps, enhancing precision fluid delivery and enabling accurate plunger position feedback. This overcomes limitations of stepper motors, improving reliability even during power interruptions.

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Area of Science:

  • Biomedical Engineering
  • Mechanical Engineering
  • Fluid Dynamics

Background:

  • Syringe pumps commonly use stepper motors, limiting precision fluid delivery and accurate feedback on infusion/aspiration tasks.
  • Stepper motor systems struggle to confirm correct operation after power interruptions, impacting reliability.

Purpose of the Study:

  • To develop and evaluate a linear servo-based actuator system for syringe pumps.
  • To provide absolute plunger position indication for enhanced precision and reliability in fluid delivery.

Main Methods:

  • A linear servo actuator system was designed and implemented for syringe pumps.
  • System performance was assessed using a camera tracking system.
  • Testing involved syringe capacities from 3 to 50 ml and plunger speeds from 1 to 6.6 mm/s.
  • Evaluations were conducted with distilled water, 50% glycerol-water, and Freund's adjuvant.

Main Results:

  • The linear servo system demonstrated linearity and reliability in plunger translation with distilled water and glycerol-water mixtures.
  • Testing confirmed accurate plunger position feedback across various syringe sizes and speeds.
  • Cyclical stick-slip behavior was observed with Freund's adjuvant, indicating potential limitations with highly viscous or non-Newtonian fluids.

Conclusions:

  • The linear servo actuator system offers a significant improvement over stepper motor-based syringe pumps for precision fluid delivery.
  • Absolute plunger position feedback enhances reliability and allows for verification of infusion/aspiration tasks.
  • Further research may be needed to optimize performance with complex fluid types.