Radiation Dose in Prostatic Artery Embolization Using Cone-Beam CT and 3D Roadmap Software

To evaluate the radiation dose in patients undergoing prostatic artery embolization (PAE) using cone-beam CT and 3-dimensional (3D) guidance software.

In this single-center retrospective study, 100 patients with benign prostatic hyperplasia (mean prostate volume, 83.6 mL ± 44.2; 69.4 ± 9.6 years of age; body mass index, 26.5 ± 4.2) were treated using PAE between October 2016 and April 2018. Informed consent was obtained from all participants included in the study. All patients received at least 1 intraprocedural cone-beam CT per side for evaluation of the vessel anatomy and software rendering of 3D guidance for catheter guidance. Digital subtraction angiography (DSA) was performed in the distal branches only. The total dose area product (DAP), along with the DAP attributed to fluoroscopy, DSA, and cone-beam CT, were assessed.

Bilateral embolization was achieved in 83 patients (83%). The average total DAP was 134.4 Gy ⋅ cm² ± 69.5 (range, 44.7-410.9 Gy ⋅ cm²). Fluoroscopy, DSA, and cone-beam CT accounted for 35.5 Gy ⋅ cm² ± 21.3 (range, 8.6-148.6 Gy ⋅ cm²) or 26.4% (percentage of total DAP), 58.2 Gy ⋅ cm² ± 48.3 (range, 10.3-309.3 Gy ⋅ cm²) or 43.3%, and 40.7 Gy ⋅ cm² ± 14.5 (range, 15.9-86.3 Gy ⋅ cm²) or 30.3%, respectively. Average procedure time was 89.4 ± 27.0 minutes, and the average fluoroscopy time was 30.9 ± 12.2 minutes.

Intraprocedural cone-beam CT in combination with 3D guidance software allows for identification and catheterization of the prostatic artery in PAE. Furthermore, the results of this trial indicate that this study protocol may lead to a low overall radiation dose.