Central serous chorioretinopathy following ingestion of sildenafil citrate

We report a case of a 35-year-old man who presented with headache followed by decreased vision, metamorphopsia, and altered color perception in his left eye, after repeated intake of sildenafil citrate (four times; 100 mg) in a limited period (3 days).

On the first ocular examination, best-corrected distance visual acuity (CDVA) was 20/80 in his left eye and 20/20 in his right eye. On fundus examination, loss of foveal reflex and serous retinal detachment in the foveal region were detected. Fluorescein angiography of the left eye was compatible with a leakage area with determined borders. The patient was advised to stop sildenafil intake.

After 4 weeks, CDVA increased to 20/25, and the fundus examination revealed significant improvement of the macular edema. Optical coherence tomography showed increased foveal thickness to 350 μm.

Advising patients with central serous chorioretinopathy to stop sildenafil intake should be considered.