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Schistosomiasis: Life Cycle, Diagnosis, and Control.
1Department of Animal Science, Nelwan Institution for Human Resource Development, Palu, Indonesia.
Current Therapeutic Research, Clinical and Experimental
|August 3, 2019
Summary
Schistosomiasis, a parasitic disease, can be diagnosed using Kato-Katz and PCR methods. Praziquantel is the current treatment, with vaccines and gene therapy offering future elimination strategies for this blood-worm infection.
Area of Science:
- Parasitology
- Infectious Diseases
- Public Health
Background:
- Schistosomiasis is a parasitic disease caused by blood-worms infecting multiple organs.
- Current elimination strategies include Praziquantel, vaccines, and gene therapy.
Purpose of the Study:
- Review progress in schistosomiasis research.
- Focus on parasite life cycle, diagnosis, and control strategies.
Main Methods:
- PubMed Database search (2014-2018).
- Included open-access English articles.
Main Results:
- Schistosomiasis involves snails and mammals; manifestations are acute or chronic.
- Infection sites include liver, intestine, bladder, and urethra, with species-specific symptoms.
- Kato-Katz and PCR are key diagnostic tools; Praziquantel is the primary treatment.
Conclusions:
- Kato-Katz and PCR are effective for schistosomiasis detection.
- Praziquantel, improved diagnostics, vaccines, and gene therapy are crucial for disease elimination.
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