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Keratoconus progression associated with hormone replacement therapy
Giulia Coco1,2, Ahmad Kheirkhah1, William Foulsham1
1Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
Purpose:
To report a postmenopausal patient with keratoconus who experienced significant progression after using hormone replacement therapy.
Observations:
A 51-year-old woman with previously stable keratoconus presented with acute disease progression following hormone replacement therapy in the context of prophylactic hysterectomy and bilateral ovariosalpingectomy. Over a 14-month period after starting hormone therapy, the steepest K increased from 63.7D to 71.5D in the right eye and from 65.8D to 78.1D in the left eye.
Conclusions:
Hormone replacement therapy may amplify progression of keratoconus.
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