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Keratoconus progression associated with hormone replacement therapy.

Giulia Coco1,2, Ahmad Kheirkhah1, William Foulsham1

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American Journal of Ophthalmology Case Reports
|August 3, 2019
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Summary
This summary is machine-generated.

Hormone replacement therapy may worsen keratoconus progression in postmenopausal women. This case study highlights a patient with rapid vision changes after starting hormone therapy.

Keywords:
Hormone replacement therapyKeratoconusKeratoconus progression

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Area of Science:

  • Ophthalmology
  • Endocrinology

Background:

  • Keratoconus is a progressive eye condition affecting corneal shape.
  • Hormone replacement therapy (HRT) is used to manage menopausal symptoms.

Observation:

  • A 51-year-old postmenopausal woman with stable keratoconus initiated HRT after surgery.
  • She experienced acute keratoconus progression within 14 months of starting HRT.

Findings:

  • Corneal steepening significantly increased in both eyes.
  • Right eye: steepest K from 63.7D to 71.5D.
  • Left eye: steepest K from 65.8D to 78.1D.

Implications:

  • HRT might exacerbate keratoconus progression.
  • Further research is needed to understand the link between HRT and keratoconus.
  • Ophthalmologists should consider HRT use in postmenopausal women with keratoconus.