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Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Infectious Diseases

Background:

  • Seasonal Hyperacute Panuveitis (SHAPU) is a rare, severe intraocular inflammatory disease endemic to Nepal.
  • SHAPU typically affects children and occurs in odd-numbered years following the monsoon season.
  • While predominantly seen in children, SHAPU has been reported in individuals up to 50 years old.

Observation:

  • A 38-day-old infant presented with acute redness and inflammation in the right eye.
  • Ocular examination revealed significant anterior chamber reaction and a white pupillary reflex.
  • Ocular ultrasonography indicated vitreous opacities and choroidal thickening.

Findings:

  • The infant underwent vitrectomy, lensectomy, and intravitreal antibiotics and steroids.
  • Microbiological and viral investigations of vitreous samples were negative for pathogens.
  • The infant's intraocular inflammation improved following treatment, with visible fundal glow.

Implications:

  • This case demonstrates that SHAPU can affect extremely young infants, as early as 38 days old.
  • The suspected link between SHAPU and exposure to moths remains a significant etiological consideration.
  • Early diagnosis and prompt intervention are crucial for managing SHAPU in infants.