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Updated: Jan 21, 2026

Preparation of DNA-crosslinked Polyacrylamide Hydrogels
Published on: August 27, 2014
Reversible hydrogel dynamics by physical-chemical crosslink photoswitching using a supramolecular macrocycle template
1Department of Chemical & Biomolecular Engineering, University of Notre Dame, Notre Dame, IN 46556, USA. mwebber@nd.edu.
Abstract:
Cucurbit[8]uril catalyzes reversible photodimerization of polymer-appended guests, transitioning hydrogel crosslinking from physical to chemical networks. The process of photodimerization is partially reversible, yielding materials with hybrid emergent properties, and which can also be patterned. Accordingly, hydrogels with externally controlled network dynamics are demonstrated.
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