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Updated: Jan 21, 2026

Assembly, Loading, and Alignment of an Analytical Ultracentrifuge Sample Cell
Published on: November 5, 2009
Architecture and Assembly of Periplasmic Flagellum
Yunjie Chang1,2, Jun Liu1,2
1Microbial Sciences Institute University, West Haven, CT 06516.
Abstract:
Periplasmic flagella are complex nanomachines responsible for distinctive morphology and motility of spirochetes. Although bacterial flagella have been extensively studied for several decades in the model systems Escherichia coli and Salmonella enterica, our understanding of periplasmic flagella in many disease-causing spirochetes remains incomplete. Recent advances, including molecular genetics, biochemistry, structural biology, and cryo-electron tomography, have greatly increased our understanding of structure and function of periplasmic flagella. In this chapter, we summarize some of the recent findings that provide new insights into the structure, assembly, and function of periplasmic flagella.
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